Title: Neural coupling of cooperative hand movements : a reflex and fMRI study
Authors : Dietz, Volker
Macauda, Gianluca
Schrafl-Altermatt, Miriam
Wirz, Markus
Kloter, Evelyne
Michels, Lars
Published in : Cerebral cortex
Volume(Issue) : 25
Issue : 4
Pages : 948
Pages to: 958
Publisher / Ed. Institution : Oxford University Press
Issue Date: 2015
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (publication)
Language : English
Subjects : Bilateral reflex responses; Hand function; Motor control; Secondary somatosensory cortex; Unilateral nerve stimulation; Adult; Biomechanical Phenomena; Brain; Brain Mapping; Electric Stimulation; Electromyography; Female; Functional Laterality; Hand; Humans; Isometric Contraction; Magnetic Resonance Imaging; Male; Movement; Muscle, Skeletal; Neural Pathways; Psychophysics; Reflex; Torque; Ulnar Nerve
Subject (DDC) : 610: Medicine and health
Abstract: The neural control of "cooperative" hand movements reflecting "opening a bottle" was explored in human subjects by electromyographic (EMG) and functional magnetic resonance imaging (fMRI) recordings. EMG responses to unilateral nonnoxious ulnar nerve stimulation were analyzed in the forearm muscles of both sides during dynamic movements against a torque applied by the right hand to a device which was compensated for by the left hand. For control, stimuli were applied while task was performed in a static/isometric mode and during bilateral synchronous pro-/supination movements. During the dynamic cooperative task, EMG responses to stimulations appeared in the right extensor and left flexor muscles, regardless of which side was stimulated. Under the control conditions, responses appeared only on the stimulated side. fMRI recordings showed a bilateral extra-activation and functional coupling of the secondary somatosensory cortex (S2) during the dynamic cooperative, but not during the control, tasks. This activation might reflect processing of shared cutaneous input during the cooperative task. Correspondingly, it is assumed that stimulation-induced unilateral volleys are processed in S2, leading to a release of EMG responses to both forearms. This indicates a task-specific neural coupling during cooperative hand movements, which has consequences for the rehabilitation of hand function in poststroke patients.
Departement: Health Professions
Organisational Unit: Institute of Physiotherapy (IPT)
Publication type: Article in scientific journal
DOI : 10.1093/cercor/bht285
ISSN: 1460-2199
1047-3211
URI: https://digitalcollection.zhaw.ch/handle/11475/14539
Appears in Collections:Publikationen Gesundheit

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