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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-28382
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dc.contributor.authorMatesanz, Luis-
dc.contributor.authorHausheer, Andrea C.-
dc.contributor.authorBaskozos, Georgios-
dc.contributor.authorBennett, David L. H.-
dc.contributor.authorSchmid, Annina B.-
dc.date.accessioned2023-08-04T08:41:40Z-
dc.date.available2023-08-04T08:41:40Z-
dc.date.issued2021-04-
dc.identifier.issn0304-3959de_CH
dc.identifier.issn1872-6623de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/28382-
dc.description.abstractIt currently remains unclear why some patients with entrapment neuropathies develop neuropathic pain (neuP), whereas others have non-neuP, presumably of nociceptive character. Studying patients with carpal tunnel syndrome (CTS), this cross-sectional cohort study investigated changes in somatosensory structure and function as well as emotional well-being specific to the presence and severity of neuP. Patients with CTS (n = 108) were subgrouped by the DN4 questionnaire into those without and with neuP. The latter group was further subdivided into mild and moderate/severe neuP using a pain visual analogue scale. N = 32 participants served as healthy controls. All participants underwent a clinical examination, quantitative sensory testing, electrodiagnostic testing (EDT), and skin biopsy to determine the structural integrity of dermal and intraepidermal nerve fibres. Patients also completed questionnaires evaluating symptom severity and functional deficits, pain distribution, sleep quality, and emotional well-being. The overall prevalence of neuP in patients with CTS was 80%, of which 63% had mild neuP. Symptom severity and functional deficits as well as somatosensory dysfunction was more pronounced with the presence and increasing severity of neuP. No difference was identified among patient groups for EDT and nerve fibre integrity on biopsies. The severity of neuP was accompanied by more pronounced deficits in emotional well-being and sleep quality. Intriguingly, extraterritorial spread of symptoms was more prevalent in patients with moderate/severe neuP, indicating the presence of central mechanisms. NeuP is common in patients with CTS, and its severity is related to the extent of somatosensory dysfunction and a compromise of emotional well-being.de_CH
dc.language.isoende_CH
dc.publisherLippincott Williams & Wilkinsde_CH
dc.relation.ispartofPainde_CH
dc.rightshttps://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectCross-sectional studiesde_CH
dc.subjectPhenotypede_CH
dc.subjectNerve compression syndromede_CH
dc.subjectNeuralgiade_CH
dc.subjectNeuropathic painde_CH
dc.subjectQuantitative sensory testingde_CH
dc.subjectEntrapment neuropathyde_CH
dc.subjectCarpal tunnel syndromede_CH
dc.subject.ddc616.8: Neurologie und Krankheiten des Nervensystemsde_CH
dc.titleSomatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathyde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Physiotherapie (IPT)de_CH
dc.identifier.doi10.1097/j.pain.0000000000002102de_CH
dc.identifier.doi10.21256/zhaw-28382-
dc.identifier.pmid33044393de_CH
zhaw.funding.euNode_CH
zhaw.issue4de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end1220de_CH
zhaw.pages.start1211de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume162de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Matesanz, L., Hausheer, A. C., Baskozos, G., Bennett, D. L. H., & Schmid, A. B. (2021). Somatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathy. Pain, 162(4), 1211–1220. https://doi.org/10.1097/j.pain.0000000000002102
Matesanz, L. et al. (2021) ‘Somatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathy’, Pain, 162(4), pp. 1211–1220. Available at: https://doi.org/10.1097/j.pain.0000000000002102.
L. Matesanz, A. C. Hausheer, G. Baskozos, D. L. H. Bennett, and A. B. Schmid, “Somatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathy,” Pain, vol. 162, no. 4, pp. 1211–1220, Apr. 2021, doi: 10.1097/j.pain.0000000000002102.
MATESANZ, Luis, Andrea C. HAUSHEER, Georgios BASKOZOS, David L. H. BENNETT und Annina B. SCHMID, 2021. Somatosensory and psychological phenotypes associated with neuropathic pain in entrapment neuropathy. Pain. April 2021. Bd. 162, Nr. 4, S. 1211–1220. DOI 10.1097/j.pain.0000000000002102
Matesanz, Luis, Andrea C. Hausheer, Georgios Baskozos, David L. H. Bennett, and Annina B. Schmid. 2021. “Somatosensory and Psychological Phenotypes Associated with Neuropathic Pain in Entrapment Neuropathy.” Pain 162 (4): 1211–20. https://doi.org/10.1097/j.pain.0000000000002102.
Matesanz, Luis, et al. “Somatosensory and Psychological Phenotypes Associated with Neuropathic Pain in Entrapment Neuropathy.” Pain, vol. 162, no. 4, Apr. 2021, pp. 1211–20, https://doi.org/10.1097/j.pain.0000000000002102.


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