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dc.contributor.authorHubli, Michèle-
dc.contributor.authorBolt, Doris-
dc.contributor.authorKrassioukov, Andrei V-
dc.date.accessioned2022-09-12T08:16:30Z-
dc.date.available2022-09-12T08:16:30Z-
dc.date.issued2017-
dc.identifier.issn1362-4393de_CH
dc.identifier.issn1476-5624de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/25609-
dc.description.abstractStudy design : Systematic review. Objectives : A spinal cord injury (SCI) commonly results in alterations of cardiovascular physiology. In order to investigate such alterations, the cold pressor test (CPT) has been used as an established challenge test. This review summarizes the basic physiology underlying a CPT, discusses potential mechanisms responsible for abnormal pressor responses following SCI, and highlights the utility of CPT in the SCI population. Setting : Canada and Switzerland. Methods : we have completed a comprehensive review of studies that have investigated the effect of foot or hand CPT on hemodynamic indices in individuals with SCI. Results : Depending on the level of spinal cord lesion and the location of cold application, i.e., above or below the lesion, mean arterial pressure typically increases (ranging between 4 and 23 mmHg), while heart rate responses demonstrated either a decrease or an increase (ranging between −4 and 24 bpm) during CPT. The increase in blood pressure during foot CPT in high-level lesions might not necessarily be attributed to a physiological CPT response as seen in able-bodied individuals, but rather due to a reflexic sympathetic discharge below the level of lesion, known as autonomic dysreflexia. Conclusions : Further investigations in a wider range of individuals with SCI including incomplete injuries might be helpful to examine the ability of CPT assessing the integrity of the autonomic nervous system following SCI. Furthermore, additional autonomic tests are needed to emphasize the integrity of autonomic pathways and to account for the complexity of the autonomic nervous system.de_CH
dc.language.isoende_CH
dc.publisherNature Publishing Groupde_CH
dc.relation.ispartofSpinal Cordde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectAutonomic nervous system diseasede_CH
dc.subjectFootde_CH
dc.subjectHandde_CH
dc.subjectHumande_CH
dc.subjectSpinal cord injuryde_CH
dc.subjectCold temperaturede_CH
dc.subjectHemodynamicde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.subject.ddc617: Chirurgiede_CH
dc.titleCold pressor test in spinal cord injury – revisitedde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Physiotherapie (IPT)de_CH
dc.identifier.doi10.1038/s41393-017-0037-zde_CH
dc.identifier.pmid29259348de_CH
zhaw.funding.euNode_CH
zhaw.issue6de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end537de_CH
zhaw.pages.start528de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume56de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Gesundheit

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Hubli, M., Bolt, D., & Krassioukov, A. V. (2017). Cold pressor test in spinal cord injury – revisited. Spinal Cord, 56(6), 528–537. https://doi.org/10.1038/s41393-017-0037-z
Hubli, M., Bolt, D. and Krassioukov, A.V. (2017) ‘Cold pressor test in spinal cord injury – revisited’, Spinal Cord, 56(6), pp. 528–537. Available at: https://doi.org/10.1038/s41393-017-0037-z.
M. Hubli, D. Bolt, and A. V. Krassioukov, “Cold pressor test in spinal cord injury – revisited,” Spinal Cord, vol. 56, no. 6, pp. 528–537, 2017, doi: 10.1038/s41393-017-0037-z.
HUBLI, Michèle, Doris BOLT und Andrei V KRASSIOUKOV, 2017. Cold pressor test in spinal cord injury – revisited. Spinal Cord. 2017. Bd. 56, Nr. 6, S. 528–537. DOI 10.1038/s41393-017-0037-z
Hubli, Michèle, Doris Bolt, and Andrei V Krassioukov. 2017. “Cold Pressor Test in Spinal Cord Injury – Revisited.” Spinal Cord 56 (6): 528–37. https://doi.org/10.1038/s41393-017-0037-z.
Hubli, Michèle, et al. “Cold Pressor Test in Spinal Cord Injury – Revisited.” Spinal Cord, vol. 56, no. 6, 2017, pp. 528–37, https://doi.org/10.1038/s41393-017-0037-z.


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