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dc.contributor.authorEtzweiler, Denise-
dc.contributor.authorAlbisetti, Manuela-
dc.contributor.authorMeichtry, André-
dc.contributor.authorHuber, Erika-
dc.date.accessioned2021-08-26T10:41:14Z-
dc.date.available2021-08-26T10:41:14Z-
dc.date.issued2021-07-
dc.identifier.issn1351-8216de_CH
dc.identifier.issn1365-2516de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/23012-
dc.description.abstractIntroduction: Despite adequate medical treatment, many young adults with haemophilia develop joint alterations—especially in ankles and knees. Undetected over years, subtle structural changes cause subclinical symptoms, before problems become obvious. To objectify these silent pressure pains, the pressure pain threshold (PPT) can be measured by algometry. Aim: The aim was to investigate and compare the effect of age on PPTs in asymptomatic ankles and knees between boys and young adults with haemophilia and age-matched controls, in order to gain better knowledge about the alteration of the periarticular structures with increasing age. Material and methods: Nineteen persons with haemophilia (PwH; severe or moderate; 8–30 years) and 19 age-matched controls with ‘healthy’ ankles and knees were recruited. Asymptomatic joints with a Haemophilia Joint Health Score = 0 were included. The PPT was measured on four periarticular points per joint, and the data were analysed with a linear mixed model. Results: The PPT of the control group increased with age, whereas the PPT of the PwH decreased. The difference in age effect per year in kPa between PwH and controls was as follows: β [95%-CI]: −15.41 [−31.63; 0.79]. Although the result was not statistically significant (p = .08), a clear tendency was shown. Conclusion: The results suggest that subclinical alterations in the periarticular structures of these joints may evolve unnoticed over time. However, further research is warranted to determine whether this observed trend is confirmed in a larger sample and at what age the PPT begins to decrease in PwH compared to controls.de_CH
dc.language.isoende_CH
dc.publisherWileyde_CH
dc.relation.ispartofHaemophiliade_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectHaemophiliade_CH
dc.subjectYoungde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleThe effect of age on the pressure pain threshold of asymptomatic ankles and knees in young individuals with haemophiliade_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Physiotherapie (IPT)de_CH
dc.identifier.doi10.1111/hae.14344de_CH
zhaw.funding.euNode_CH
zhaw.issue4de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end689de_CH
zhaw.pages.start683de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume27de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Gesundheit

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