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dc.contributor.authorCurjuric, Ivan-
dc.contributor.authorImboden, Medea-
dc.contributor.authorBettschart, Robert-
dc.contributor.authorCaviezel, Seraina-
dc.contributor.authorDratva, Julia-
dc.contributor.authorPons, Marco-
dc.contributor.authorRothe, Thomas-
dc.contributor.authorSchmidt-Trucksäss, Arno-
dc.contributor.authorStolz, Daiana-
dc.contributor.authorThun, Gian Andri-
dc.contributor.authorvon Eckardstein, Arnold-
dc.contributor.authorKronenberg, Florian-
dc.contributor.authorFerrarotti, Ilaria-
dc.contributor.authorProbst-Hensch, Nicole M-
dc.date.accessioned2019-07-22T09:27:05Z-
dc.date.available2019-07-22T09:27:05Z-
dc.date.issued2018-
dc.identifier.issn1879-1484de_CH
dc.identifier.issn0021-9150de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/17594-
dc.description.abstractAlpha-1 antitrypsin (A1AT) is the most abundant serine protease inhibitor in human blood and exerts important anti-inflammatory and immune-modulatory effects. In combination with smoking or other long-term noxious exposures such as occupational dust and fumes, genetic A1AT deficiency can cause chronic obstructive pulmonary disease, a condition with elevated cardiovascular risk. The effects of A1AT deficiency on cardiovascular risk have hardly been studied today.de_CH
dc.language.isoende_CH
dc.publisherElsevierde_CH
dc.relation.ispartofAtherosclerosisde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectAlpha-1 antitrypsin deficiencyde_CH
dc.subjectCardiovascular diseasede_CH
dc.subjectCohort studyde_CH
dc.subjectMESH): carotid intima-media thicknessde_CH
dc.subjectMendelian randomization analysisde_CH
dc.subjectAgedde_CH
dc.subjectBlood pressurede_CH
dc.subjectCarotid artery diseasede_CH
dc.subjectCarotid intima-media thicknessde_CH
dc.subjectFemalede_CH
dc.subjectGenetic predisposition to diseasede_CH
dc.subjectHumande_CH
dc.subjectHypertensionde_CH
dc.subjectMalede_CH
dc.subjectMendelian randomization analysisde_CH
dc.subjectMiddle agedde_CH
dc.subjectPhenotypede_CH
dc.subjectPulmonary disease, chronic obstructivede_CH
dc.subjectRisk assessmentde_CH
dc.subjectRisk factorde_CH
dc.subjectSwitzerlandde_CH
dc.subjectalpha 1-antitrypsinde_CH
dc.subjectalpha 1-antitrypsin deficiencyde_CH
dc.subjectMutationde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleAlpha-1 antitrypsin deficiency : from the lung to the heart?de_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Public Health (IPH)de_CH
dc.identifier.doi10.1016/j.atherosclerosis.2018.01.042de_CH
dc.identifier.pmid29432934de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end172de_CH
zhaw.pages.start166de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume270de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
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Curjuric, I., Imboden, M., Bettschart, R., Caviezel, S., Dratva, J., Pons, M., Rothe, T., Schmidt-Trucksäss, A., Stolz, D., Thun, G. A., von Eckardstein, A., Kronenberg, F., Ferrarotti, I., & Probst-Hensch, N. M. (2018). Alpha-1 antitrypsin deficiency : from the lung to the heart? Atherosclerosis, 270, 166–172. https://doi.org/10.1016/j.atherosclerosis.2018.01.042
Curjuric, I. et al. (2018) ‘Alpha-1 antitrypsin deficiency : from the lung to the heart?’, Atherosclerosis, 270, pp. 166–172. Available at: https://doi.org/10.1016/j.atherosclerosis.2018.01.042.
I. Curjuric et al., “Alpha-1 antitrypsin deficiency : from the lung to the heart?,” Atherosclerosis, vol. 270, pp. 166–172, 2018, doi: 10.1016/j.atherosclerosis.2018.01.042.
CURJURIC, Ivan, Medea IMBODEN, Robert BETTSCHART, Seraina CAVIEZEL, Julia DRATVA, Marco PONS, Thomas ROTHE, Arno SCHMIDT-TRUCKSÄSS, Daiana STOLZ, Gian Andri THUN, Arnold VON ECKARDSTEIN, Florian KRONENBERG, Ilaria FERRAROTTI und Nicole M PROBST-HENSCH, 2018. Alpha-1 antitrypsin deficiency : from the lung to the heart? Atherosclerosis. 2018. Bd. 270, S. 166–172. DOI 10.1016/j.atherosclerosis.2018.01.042
Curjuric, Ivan, Medea Imboden, Robert Bettschart, Seraina Caviezel, Julia Dratva, Marco Pons, Thomas Rothe, et al. 2018. “Alpha-1 Antitrypsin Deficiency : From the Lung to the Heart?” Atherosclerosis 270: 166–72. https://doi.org/10.1016/j.atherosclerosis.2018.01.042.
Curjuric, Ivan, et al. “Alpha-1 Antitrypsin Deficiency : From the Lung to the Heart?” Atherosclerosis, vol. 270, 2018, pp. 166–72, https://doi.org/10.1016/j.atherosclerosis.2018.01.042.


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