| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients |
| Autor/-in: | Zipser, Carl Moritz Deuel, Jeremy Ernst, Jutta Schubert, Maria von Känel, Roland Böttger, Sönke |
| et. al: | No |
| DOI: | 10.1007/s00701-019-03927-z |
| Erschienen in: | Acta Neurochirurgica |
| Band(Heft): | 161 |
| Heft: | 7 |
| Seite(n): | 1307 |
| Seiten bis: | 1315 |
| Erscheinungsdatum: | 2019 |
| Verlag / Hrsg. Institution: | Springer |
| ISSN: | 0001-6268 0942-0940 |
| Sprache: | Englisch |
| Schlagwörter: | Delirium; Impact; Interaction; Neurosurgery; Precipitating factor; Predisposing factor; Risk factor |
| Fachgebiet (DDC): | 617: Chirurgie |
| Zusammenfassung: | Background: Delirium is the most common neuropsychiatric presentation during hospitalization. In neurosurgery, studies on predisposing and precipitating risk factors for the development of delirium are rare but required for the individual risk estimation. Methods: Prospective cohort study in a tertiary university center. In total, 949 neurosurgical patients, 307 with and 642 without delirium, were included. Demographic factors, neurosurgery-related, neurological, and medical clusters were tested as predictors of delirium in multiple logistic regression analyses. Results: The incidence of delirium in this cohort of neurosurgical patients was 32.4%. Compared to patients without delirium, those with delirium were significantly older, more cognitively and neurologically impaired, transferred from hospitals and nursing homes, admitted as emergencies, longer hospitalized (16.2 vs. 9.5 days; p < 0.001), in greater need of intensive care management, and more frequently transferred to rehabilitation. Predisposing factors of delirium were stroke (OR 5.45, CI 2.12–14.0, p < 0.001), cardiac insufficiency (OR 4.59, CI 1.09–19.26, p = 0.038), cerebral neoplasm (OR 1.53, CI 0.92–2.54, p = 0.019), and age ≥ 65 years (OR 1.47, CI 1.03–2.09, p = 0.030). Precipitating factors of delirium were acute cerebral injury (OR 3.91, CI 2.24–6.83, p < 0.001), hydrocephalus (OR 3.10, CI 1.98–4.87, p < 0.001), and intracranial hemorrhage (OR 1.90, CI 1.23–2.94, p = 0.004). Conclusions: Delirium in acute neurosurgical patients was associated with longer hospitalization. Whereas common etiologies of delirium like infections and dementia, did not predict delirium, preexisting neurovascular and traumatic diseases, as well as surgery-related events seem important risk factors contributing to delirium in neurosurgery. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/17507 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | Gesundheit |
| Organisationseinheit: | Institut für Pflege (IPF) |
| Enthalten in den Sammlungen: | Publikationen Gesundheit |
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Zipser, C. M., Deuel, J., Ernst, J., Schubert, M., von Känel, R., & Böttger, S. (2019). The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients. Acta Neurochirurgica, 161(7), 1307–1315. https://doi.org/10.1007/s00701-019-03927-z
Zipser, C.M. et al. (2019) ‘The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients’, Acta Neurochirurgica, 161(7), pp. 1307–1315. Available at: https://doi.org/10.1007/s00701-019-03927-z.
C. M. Zipser, J. Deuel, J. Ernst, M. Schubert, R. von Känel, and S. Böttger, “The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients,” Acta Neurochirurgica, vol. 161, no. 7, pp. 1307–1315, 2019, doi: 10.1007/s00701-019-03927-z.
ZIPSER, Carl Moritz, Jeremy DEUEL, Jutta ERNST, Maria SCHUBERT, Roland VON KÄNEL und Sönke BÖTTGER, 2019. The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients. Acta Neurochirurgica. 2019. Bd. 161, Nr. 7, S. 1307–1315. DOI 10.1007/s00701-019-03927-z
Zipser, Carl Moritz, Jeremy Deuel, Jutta Ernst, Maria Schubert, Roland von Känel, and Sönke Böttger. 2019. “The Predisposing and Precipitating Risk Factors for Delirium in Neurosurgery : A Prospective Cohort Study of 949 Patients.” Acta Neurochirurgica 161 (7): 1307–15. https://doi.org/10.1007/s00701-019-03927-z.
Zipser, Carl Moritz, et al. “The Predisposing and Precipitating Risk Factors for Delirium in Neurosurgery : A Prospective Cohort Study of 949 Patients.” Acta Neurochirurgica, vol. 161, no. 7, 2019, pp. 1307–15, https://doi.org/10.1007/s00701-019-03927-z.
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