Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage

Zhang, Xuequn; Deckert, Volker; Steiger, Beat; Hirayama, Martina; Suter, Ulrich; Pretsch, Ernö

doi:10.1016/j.talanta.2003.11.043

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage
Authors:	Zhang, Xuequn Deckert, Volker Steiger, Beat Hirayama, Martina Suter, Ulrich Pretsch, Ernö
DOI:	10.1016/j.talanta.2003.11.043
Published in:	Talanta
Volume(Issue):	63
Issue:	1
Page(s):	159
Pages to:	165
Issue Date:	May-2004
Publisher / Ed. Institution:	Elsevier
Publisher / Ed. Institution:	Amsterdam
ISSN:	0039-9140 1873-3573
Language:	English
Subjects:	Polysiloxane; Biosensor; Biorecognition; Immobilization
Subject (DDC):	540: Chemistry
Abstract:	By activating Si-H bonds, poly(hydromethylsiloxane) can be covalently bound in a first step to various metal or polymer surfaces. In a second step, unreacted Si-H bonds can be brought to react with organic compounds having adequate functional groups such as double or triple bonds, carbonyl or hydroxyl groups. This scheme is used to bind biorecognition groups to solids. The novel concept is demonstrated by attaching a newly synthesized biotin derivative to Au. It is shown that the immobilized biotin is capable of binding streptavidin.
URI:	https://digitalcollection.zhaw.ch/handle/11475/3025
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Engineering
Appears in collections:	Publikationen School of Engineering

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Zhang, X., Deckert, V., Steiger, B., Hirayama, M., Suter, U., & Pretsch, E. (2004). Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage. Talanta, 63(1), 159–165. https://doi.org/10.1016/j.talanta.2003.11.043

Zhang, X. et al. (2004) ‘Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage’, Talanta, 63(1), pp. 159–165. Available at: https://doi.org/10.1016/j.talanta.2003.11.043.

X. Zhang, V. Deckert, B. Steiger, M. Hirayama, U. Suter, and E. Pretsch, “Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage,” Talanta, vol. 63, no. 1, pp. 159–165, May 2004, doi: 10.1016/j.talanta.2003.11.043.

ZHANG, Xuequn, Volker DECKERT, Beat STEIGER, Martina HIRAYAMA, Ulrich SUTER und Ernö PRETSCH, 2004. Covalent binding of biorecognition groups to solids using poly(hydromethylsiloxane) as linkage. Talanta. Mai 2004. Bd. 63, Nr. 1, S. 159–165. DOI 10.1016/j.talanta.2003.11.043

Zhang, Xuequn, Volker Deckert, Beat Steiger, Martina Hirayama, Ulrich Suter, and Ernö Pretsch. 2004. “Covalent Binding of Biorecognition Groups to Solids Using Poly(hydromethylsiloxane) as Linkage.” Talanta 63 (1): 159–65. https://doi.org/10.1016/j.talanta.2003.11.043.

Zhang, Xuequn, et al. “Covalent Binding of Biorecognition Groups to Solids Using Poly(hydromethylsiloxane) as Linkage.” Talanta, vol. 63, no. 1, May 2004, pp. 159–65, https://doi.org/10.1016/j.talanta.2003.11.043.