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https://doi.org/10.21256/zhaw-1600| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Immunomodulation by zearalenone in carp (Cyprinus carpio L.) |
| Autor/-in: | Pietsch-Schmied, Constanze Junge, Ranka Burkhardt-Holm, Patricia |
| DOI: | 10.21256/zhaw-1600 10.1155/2015/420702 |
| Erschienen in: | BioMed Research International |
| Band(Heft): | 2015 |
| Heft: | 420702 |
| Erscheinungsdatum: | 2015 |
| Verlag / Hrsg. Institution: | Hindawi |
| ISSN: | 2314-6133 2314-6141 |
| Sprache: | Englisch |
| Schlagwörter: | Mycotoxin; Immune system; Carp; Aquaculture |
| Fachgebiet (DDC): | 572: Biochemie |
| Zusammenfassung: | The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feeds, but its effects on fish have not yet been investigated extensively. In order to fill this gap a feeding trial with juvenile carp was conducted. Three groups of fish were fed feeds contaminated with ZEN at three concentrations (low: 332 mg kg-1, medium: 621 mg kg-1, and high: 797 mg kg-1 feed) for four weeks. Possible reversible effects of ZEN were evaluated by feeding an additional group with the ZEN-contaminated feeds for four weeks, followed by the uncontaminated diet for two weeks. Immune function of isolated leukocytes from head kidney and trunk kidney was assessed using the assessment of NO production, the respiratory burst assay, the chemiluminescence assay and the measurement of arginase activities. These investigations frequently revealed increased immune responses after exposure of fish to low ZEN concentrations and reduced immune responses after exposure to high mycotoxin concentrations. Moreover, the feeding of the uncontaminated diet for further two weeks did not improve the immune responses in most cases. These results indicate that cellular immune functions in ZEN-contaminated carp are profoundly influenced which may be relevant for fish health in aquaculture. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2361 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | CC BY 3.0: Namensnennung 3.0 Unported |
| Departement: | Life Sciences und Facility Management |
| Organisationseinheit: | Institut für Umwelt und Natürliche Ressourcen (IUNR) |
| Enthalten in den Sammlungen: | Publikationen Life Sciences und Facility Management |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| 2015_Pietsch-Schmied_Immunomodulation by zearalenone in carp_BioMed Research International.pdf | 2.14 MB | Adobe PDF |  Öffnen/Anzeigen |
Zur Langanzeige
Pietsch-Schmied, C., Junge, R., & Burkhardt-Holm, P. (2015). Immunomodulation by zearalenone in carp (Cyprinus carpio L.). BioMed Research International, 2015(420702). https://doi.org/10.21256/zhaw-1600
Pietsch-Schmied, C., Junge, R. and Burkhardt-Holm, P. (2015) ‘Immunomodulation by zearalenone in carp (Cyprinus carpio L.)’, BioMed Research International, 2015(420702). Available at: https://doi.org/10.21256/zhaw-1600.
C. Pietsch-Schmied, R. Junge, and P. Burkhardt-Holm, “Immunomodulation by zearalenone in carp (Cyprinus carpio L.),” BioMed Research International, vol. 2015, no. 420702, 2015, doi: 10.21256/zhaw-1600.
PIETSCH-SCHMIED, Constanze, Ranka JUNGE und Patricia BURKHARDT-HOLM, 2015. Immunomodulation by zearalenone in carp (Cyprinus carpio L.). BioMed Research International. 2015. Bd. 2015, Nr. 420702. DOI 10.21256/zhaw-1600
Pietsch-Schmied, Constanze, Ranka Junge, and Patricia Burkhardt-Holm. 2015. “Immunomodulation by Zearalenone in Carp (Cyprinus Carpio L.).” BioMed Research International 2015 (420702). https://doi.org/10.21256/zhaw-1600.
Pietsch-Schmied, Constanze, et al. “Immunomodulation by Zearalenone in Carp (Cyprinus Carpio L.).” BioMed Research International, vol. 2015, no. 420702, 2015, https://doi.org/10.21256/zhaw-1600.
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