| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors |
| Autor/-in: | Kaiser, Stephan Jossen, Valentin Schirmaier, Carmen Eibl, Dieter Brill, Silke van den Bos, Christian Eibl-Schindler, Regine |
| DOI: | 10.1002/cite.201200180 |
| Erschienen in: | Chemie Ingenieur Technik |
| Band(Heft): | 85 |
| Heft: | 1-2 |
| Seite(n): | 95 |
| Seiten bis: | 102 |
| Erscheinungsdatum: | Feb-2013 |
| Verlag / Hrsg. Institution: | Wiley |
| Verlag / Hrsg. Institution: | Weinheim |
| ISSN: | 0009-286X 1522-2640 |
| Sprache: | Englisch |
| Fachgebiet (DDC): | 660: Technische Chemie |
| Zusammenfassung: | The fluid flow and suspension characteristics inside small-scale, stirred, single-use bioreactors were investigated experimentally and by means of computational fluid dynamics. The required impeller speeds for homogenous suspension were determined for two microcarrier types. The shear stress level and turbulence distribution were predicted using a numerical model, which was verified by particle image velocimetry measurements. In subsequent cultivations of primary mesenchymal adipose-derived stem cells, up to 31.4-fold expansion in cell number was achieved for serum concentrations as low as 5 %. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2239 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | Life Sciences und Facility Management |
| Organisationseinheit: | Institut für Chemie und Biotechnologie (ICBT) |
| Enthalten in den Sammlungen: | Publikationen Life Sciences und Facility Management |
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Kaiser, S., Jossen, V., Schirmaier, C., Eibl, D., Brill, S., van den Bos, C., & Eibl-Schindler, R. (2013). Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors. Chemie Ingenieur Technik, 85(1-2), 95–102. https://doi.org/10.1002/cite.201200180
Kaiser, S. et al. (2013) ‘Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors’, Chemie Ingenieur Technik, 85(1-2), pp. 95–102. Available at: https://doi.org/10.1002/cite.201200180.
S. Kaiser et al., “Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors,” Chemie Ingenieur Technik, vol. 85, no. 1-2, pp. 95–102, Feb. 2013, doi: 10.1002/cite.201200180.
KAISER, Stephan, Valentin JOSSEN, Carmen SCHIRMAIER, Dieter EIBL, Silke BRILL, Christian VAN DEN BOS und Regine EIBL-SCHINDLER, 2013. Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors. Chemie Ingenieur Technik. Februar 2013. Bd. 85, Nr. 1-2, S. 95–102. DOI 10.1002/cite.201200180
Kaiser, Stephan, Valentin Jossen, Carmen Schirmaier, Dieter Eibl, Silke Brill, Christian van den Bos, and Regine Eibl-Schindler. 2013. “Fluid Flow and Cell Proliferation of Mesenchymal Adipose-Derived Stem Cells in Small-Scale, Stirred, Single-Use Bioreactors.” Chemie Ingenieur Technik 85 (1-2): 95–102. https://doi.org/10.1002/cite.201200180.
Kaiser, Stephan, et al. “Fluid Flow and Cell Proliferation of Mesenchymal Adipose-Derived Stem Cells in Small-Scale, Stirred, Single-Use Bioreactors.” Chemie Ingenieur Technik, vol. 85, no. 1-2, Feb. 2013, pp. 95–102, https://doi.org/10.1002/cite.201200180.
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