| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging |
| Autor/-in: | Schmid, Peter Lunkenheimer, Paul P. Redmann, Klaus Rothaus, Kai Jiang, Xiaoyi Cryer, Colin W. Järmann, Thomas Niederer, Peter Boesiger, Peter Anderson, Robert H. |
| DOI: | 10.1002/ar.20604 |
| Erschienen in: | The Anatomical Record |
| Band(Heft): | 290 |
| Heft: | 11 |
| Seite(n): | 1413 |
| Seiten bis: | 1423 |
| Erscheinungsdatum: | 2007 |
| Verlag / Hrsg. Institution: | Wiley |
| ISSN: | 1552-4884 1552-4892 0003-276X 1932-8494 |
| Sprache: | Englisch |
| Schlagwörter: | Animals; Statistical data interpretation; Diffusion Magnetic Resonance Imaging; Endocardium; Heart Ventricles; Three-dimensional imaging; Cardiac myocytes; Pericardium; Swine |
| Fachgebiet (DDC): | 570: Biologie |
| Zusammenfassung: | Pairs of cylindrical knives were used to punch semicircular slices from the left basal, sub-basal, equatorial, and apical ventricular wall of porcine hearts. The sections extended from the epicardium to the endocardium. Their semicircular shape compensated for the depth-related changing orientation of the myocytes relative to the equatorial plane. The slices were analyzed by diffusion tensor magnetic resonance imaging. The primary eigenvector of the diffusion tensor was determined in each pixel to calculate the number and angle of intrusion of the long axis of the aggregated myocytes relative to the epicardial surface. Arrays of axially sectioned aggregates were found in which 53% of the approximately two million segments evaluated intruded up to +/-15 degrees, 40% exhibited an angle of intrusion between +/-15 degrees and +/-45 degrees, and 7% exceeded an angle of +/-45 degrees, the positive sign thereby denoting an epi- to endocardial spiral in clockwise direction seen from the apex, while a negative sign denotes an anticlockwise spiral from the epicardium to the endocardium. In the basal and apical slices, the greater number of segments intruded in positive direction, while in the sub-basal and equatorial slices, negative angles of intrusion prevailed. The sampling of the primary eigenvectors was insensitive to postmortem decomposition of the tissue. In a previous histological study, we also documented the presence of large numbers of myocytes aggregated with their long axis intruding obliquely from the epicardial to the endocardial ventricular surfaces. We used magnetic resonance diffusion tensor imaging in this study to provide a comprehensive statistical analysis. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/5025 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | School of Engineering |
| Enthalten in den Sammlungen: | Publikationen School of Engineering |
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Schmid, P., Lunkenheimer, P. P., Redmann, K., Rothaus, K., Jiang, X., Cryer, C. W., Järmann, T., Niederer, P., Boesiger, P., & Anderson, R. H. (2007). Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging. The Anatomical Record, 290(11), 1413–1423. https://doi.org/10.1002/ar.20604
Schmid, P. et al. (2007) ‘Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging’, The Anatomical Record, 290(11), pp. 1413–1423. Available at: https://doi.org/10.1002/ar.20604.
P. Schmid et al., “Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging,” The Anatomical Record, vol. 290, no. 11, pp. 1413–1423, 2007, doi: 10.1002/ar.20604.
SCHMID, Peter, Paul P. LUNKENHEIMER, Klaus REDMANN, Kai ROTHAUS, Xiaoyi JIANG, Colin W. CRYER, Thomas JÄRMANN, Peter NIEDERER, Peter BOESIGER und Robert H. ANDERSON, 2007. Statistical analysis of the angle of intrusion of porcine ventricular myocytes from epicardium to endocardium using diffusion tensor magnetic resonance imaging. The Anatomical Record. 2007. Bd. 290, Nr. 11, S. 1413–1423. DOI 10.1002/ar.20604
Schmid, Peter, Paul P. Lunkenheimer, Klaus Redmann, Kai Rothaus, Xiaoyi Jiang, Colin W. Cryer, Thomas Järmann, Peter Niederer, Peter Boesiger, and Robert H. Anderson. 2007. “Statistical Analysis of the Angle of Intrusion of Porcine Ventricular Myocytes from Epicardium to Endocardium Using Diffusion Tensor Magnetic Resonance Imaging.” The Anatomical Record 290 (11): 1413–23. https://doi.org/10.1002/ar.20604.
Schmid, Peter, et al. “Statistical Analysis of the Angle of Intrusion of Porcine Ventricular Myocytes from Epicardium to Endocardium Using Diffusion Tensor Magnetic Resonance Imaging.” The Anatomical Record, vol. 290, no. 11, 2007, pp. 1413–23, https://doi.org/10.1002/ar.20604.
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