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Publikationstyp: Beitrag in wissenschaftlicher Zeitschrift
Art der Begutachtung: Peer review (Publikation)
Titel: Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy
Autor/-in: Ryll, Ulrike C.
Krumlinde-Sundholm, Lena
Verhage, Cornelia H.
Sicola, Elisa
Sgandurra, Giuseppina
Bastiaenen, Caroline H. G.
Eliasson, Ann-Christin
et. al: No
DOI: 10.1111/dmcn.14739
10.21256/zhaw-28377
Erschienen in: Developmental Medicine & Child Neurology
Band(Heft): 63
Heft: 4
Seite(n): 436
Seiten bis: 443
Erscheinungsdatum: 29-Nov-2020
Verlag / Hrsg. Institution: Wiley
ISSN: 1469-8749
Sprache: Englisch
Schlagwörter: Cerebral palsy; Hand; Infant; Mass screening; Sensitivity and specificity; Disability evaluation
Fachgebiet (DDC): 616.8: Neurologie und Krankheiten des Nervensystems
618.92: Pädiatrie
Zusammenfassung: Aim: To evaluate the sensitivity, specificity, and predictive value of the Hand Assessment for Infants (HAI) in identifying infants at risk of being diagnosed with unilateral cerebral palsy(CP), and to determine cut-off values for this purpose. Method: A convenience sample of 203 infants (106 females, 97 males) was assessed by the HAI at 3, 6, 9, and 12 months. Sensitivity, specificity, predictive values, and likelihood ratios were calculated using receiver operating characteristic curve analysis. Cut-off values were derived for different ages. The clinical outcome (unilateral CP yes/no) at 24 months or more served as an external criterion to investigate the predictive validity of HAI. Results: Half of the infants developed unilateral CP. The area under the curve ranged from0.77 (95% CI [confidence interval] 0.63–0.91) to 0.95 (95% CI 0.90–1.00) across HAI scales and age intervals. Likewise, sensitivity ranged from 63% to 93%, specificity from 62% to 91%, and accuracy from 73% to 94%. Interpretation: HAI scores demonstrated overall accuracy that ranged from very good to excellent in predicting unilateral CP in infants at risk aged between 3.5 and 12 months. This accuracy increased with age at assessment and the earliest possible prediction was at3.5 months of age, when appropriate HAI cut-off values for different ages were applied.
URI: https://digitalcollection.zhaw.ch/handle/11475/28377
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): CC BY-NC-ND 4.0: Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
Departement: Gesundheit
Enthalten in den Sammlungen:Publikationen Gesundheit

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Ryll, U. C., Krumlinde-Sundholm, L., Verhage, C. H., Sicola, E., Sgandurra, G., Bastiaenen, C. H. G., & Eliasson, A.-C. (2020). Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy. Developmental Medicine & Child Neurology, 63(4), 436–443. https://doi.org/10.1111/dmcn.14739
Ryll, U.C. et al. (2020) ‘Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy’, Developmental Medicine & Child Neurology, 63(4), pp. 436–443. Available at: https://doi.org/10.1111/dmcn.14739.
U. C. Ryll et al., “Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy,” Developmental Medicine & Child Neurology, vol. 63, no. 4, pp. 436–443, Nov. 2020, doi: 10.1111/dmcn.14739.
RYLL, Ulrike C., Lena KRUMLINDE-SUNDHOLM, Cornelia H. VERHAGE, Elisa SICOLA, Giuseppina SGANDURRA, Caroline H. G. BASTIAENEN und Ann-Christin ELIASSON, 2020. Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy. Developmental Medicine & Child Neurology. 29 November 2020. Bd. 63, Nr. 4, S. 436–443. DOI 10.1111/dmcn.14739
Ryll, Ulrike C., Lena Krumlinde-Sundholm, Cornelia H. Verhage, Elisa Sicola, Giuseppina Sgandurra, Caroline H. G. Bastiaenen, and Ann-Christin Eliasson. 2020. “Predictive Validity of the Hand Assessment for Infants in Infants at Risk of Unilateral Cerebral Palsy.” Developmental Medicine & Child Neurology 63 (4): 436–43. https://doi.org/10.1111/dmcn.14739.
Ryll, Ulrike C., et al. “Predictive Validity of the Hand Assessment for Infants in Infants at Risk of Unilateral Cerebral Palsy.” Developmental Medicine & Child Neurology, vol. 63, no. 4, Nov. 2020, pp. 436–43, https://doi.org/10.1111/dmcn.14739.


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