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Publikationstyp: Beitrag in wissenschaftlicher Zeitschrift
Art der Begutachtung: Peer review (Publikation)
Titel: Formalizing modularization and data hiding in synthetic biology
Autor/-in: Fellermann, Harold
Krasnogor, Natalio
Hadorn, Maik
Füchslin, Rudolf Marcel
DOI: 10.21256/zhaw-1657
10.1145/2667231
Erschienen in: ACM Journal on Emerging Technologies in Computing Systems
Band(Heft): 11
Heft: 3/24
Erscheinungsdatum: 2014
Verlag / Hrsg. Institution: Association for Computing Machinery
ISSN: 1550-4832
Sprache: Englisch
Fachgebiet (DDC): 572: Biochemie
Zusammenfassung: Biological systems employ compartmentalization and other co-localization strategies in order to orchestrate a multitude of biochemical processes by simultaneously enabling “data hiding” and modularization. This article presents recent research that embraces compartmentalization and co-location as an organizational programmatic principle in synthetic biological and biomimetic systems. In these systems, artificial vesicles and synthetic minimal cells are envisioned as nanoscale reactors for programmable biochemical synthesis and as chassis for molecular information processing. We present P systems, brane calculi, and the recently developed chemtainer calculus as formal frameworks providing data hiding and modularization and thus enabling the representation of highly complicated hierarchically organized compartmentalized reaction systems. We demonstrate how compartmentalization can greatly reduce the complexity required to implement computational functionality, and how addressable compartments permit the scaling-up of programmable chemical synthesis.
URI: https://digitalcollection.zhaw.ch/handle/11475/2712
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): Lizenz gemäss Verlagsvertrag
Departement: School of Engineering
Enthalten in den Sammlungen:Publikationen School of Engineering

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Fellermann, H., Krasnogor, N., Hadorn, M., & Füchslin, R. M. (2014). Formalizing modularization and data hiding in synthetic biology. ACM Journal on Emerging Technologies in Computing Systems, 11(3/24). https://doi.org/10.21256/zhaw-1657
Fellermann, H. et al. (2014) ‘Formalizing modularization and data hiding in synthetic biology’, ACM Journal on Emerging Technologies in Computing Systems, 11(3/24). Available at: https://doi.org/10.21256/zhaw-1657.
H. Fellermann, N. Krasnogor, M. Hadorn, and R. M. Füchslin, “Formalizing modularization and data hiding in synthetic biology,” ACM Journal on Emerging Technologies in Computing Systems, vol. 11, no. 3/24, 2014, doi: 10.21256/zhaw-1657.
FELLERMANN, Harold, Natalio KRASNOGOR, Maik HADORN und Rudolf Marcel FÜCHSLIN, 2014. Formalizing modularization and data hiding in synthetic biology. ACM Journal on Emerging Technologies in Computing Systems. 2014. Bd. 11, Nr. 3/24. DOI 10.21256/zhaw-1657
Fellermann, Harold, Natalio Krasnogor, Maik Hadorn, and Rudolf Marcel Füchslin. 2014. “Formalizing Modularization and Data Hiding in Synthetic Biology.” ACM Journal on Emerging Technologies in Computing Systems 11 (3/24). https://doi.org/10.21256/zhaw-1657.
Fellermann, Harold, et al. “Formalizing Modularization and Data Hiding in Synthetic Biology.” ACM Journal on Emerging Technologies in Computing Systems, vol. 11, no. 3/24, 2014, https://doi.org/10.21256/zhaw-1657.


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