| Publikationstyp: | Konferenz: Sonstiges |
| Art der Begutachtung: | Peer review (Abstract) |
| Titel: | Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity : results of a single-center, single-blinded, randomized controlled trial |
| Autor/-in: | Gloor, S. Misirlic, M. Frei-Lanter, C. Herzog, P. Müller, P. Schäfli-Thurnherr, J. Schregel, D. Lamdark, T. Wyss, R. Unger, I. Gisi, D. Greco, N. Mungo, G. Wirz, M. Raptis, D.A. Tschuor, C. Breitenstein, S. |
| et. al: | No |
| DOI: | 10.1093/bjs/znab202.015 |
| Erschienen in: | British Journal of Surgery |
| Tagungsband: | Abstracts of the 108th Annual Swiss Congress of Surgery held as a virtual meeting 1-3 June 2021 |
| Band(Heft): | 108 |
| Heft: | Supplement 4 |
| Angaben zur Konferenz: | 108th Annual Swiss Congress of Surgery, virtual, 1-3 June 2021 |
| Erscheinungsdatum: | Mai-2021 |
| Verlag / Hrsg. Institution: | Oxford University Press |
| ISSN: | 0007-1323 1365-2168 |
| Sprache: | Englisch |
| Schlagwörter: | Physical activity; Physiotherapy; Colorectal surgery; Preoperative care |
| Fachgebiet (DDC): | 615.82: Physiotherapie 617: Chirurgie |
| Zusammenfassung: | Objective: Patients undergoing major surgery are prone to a functional decline due to the impairment of muscle, cardiorespiratory and neurological function as a response to surgical stress. Currently, there are solely weak recommendations in the ERAS protocol regarding the role of preoperative physical activity and prehabilitation in patients undergoing colorectal surgery. Studies in heterogenous cohorts showed contradictory results regarding the impact of prehabilitation on the reduction of postoperative complications. This randomized controlled trial assesses the impact of prehabilitation on postoperative complications in patients undergoing colorectal surgery within an ERAS protocol. Methods: Between July 2016 and June 2019, a single-center, single-blinded , randomized controlled trial designed to test whether physiotherapeutic prehabilitation vs. normal physical activities prior to colorectal surgery may decrease morbidity within a stringent ERAS protocol was carried out. The primary endpoint was postoperative complications assessed by Comprehensive Complications Index (CCI®). Primary and secondary endpoints for both groups were analyzed and compared. Results: A total of 107 patients (54 in the pERACS and 53 in the control cohort) were included in the study and randomized. Dropout rate was 4.5% (n = 5). Mean age (SD) in the control cohort was 65 (29–86) and 66 (24–90) years in pERACS cohort. The pERACS cohort contained more female patients (40% vs. 55%, p = 0.123) and a higher percentage of colorectal adenocarcinoma (32% vs. 23%, p = 0.384) although not significant. Almost all patients underwent minimally invasive surgery in both cohorts (96% vs 98%, p = 1.000). There was no between-cohort difference in the primary outcome measure 30-day Comprehensive Complications Index (15 [0 – 49] vs. 18 [0 – 43], p = 0.059). Secondary outcome as complications assessed according to Clavien-Dindo, length of hospital stay, reoperation rate and mortality showed no difference between both cohorts. Conclusion: Routine physiotherapeutic prehabilitation cannot be recommended for patients undergoing colorectal surgery within an ERAS protocol (Grade A recommendation). To eliminate other confounders like geographical difference or difference in surgical technique, further multicenter RCTs are needed. |
| URI: | https://academic.oup.com/bjs/article/108/Supplement_4/znab202.015/6287411 https://digitalcollection.zhaw.ch/handle/11475/24270 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | Gesundheit |
| Organisationseinheit: | Institut für Physiotherapie (IPT) |
| Publiziert im Rahmen des ZHAW-Projekts: | Präoperative Physiotherapie bei kolorektalen Eingriffen |
| Enthalten in den Sammlungen: | Publikationen Gesundheit |
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Gloor, S., Misirlic, M., Frei-Lanter, C., Herzog, P., Müller, P., Schäfli-Thurnherr, J., Schregel, D., Lamdark, T., Wyss, R., Unger, I., Gisi, D., Greco, N., Mungo, G., Wirz, M., Raptis, D. A., Tschuor, C., & Breitenstein, S. (2021). Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity : results of a single-center, single-blinded, randomized controlled trial [Conference presentation]. British Journal of Surgery, 108(Supplement 4). https://doi.org/10.1093/bjs/znab202.015
Gloor, S. et al. (2021) ‘Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity : results of a single-center, single-blinded, randomized controlled trial’, in British Journal of Surgery. Oxford University Press. Available at: https://doi.org/10.1093/bjs/znab202.015.
S. Gloor et al., “Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity : results of a single-center, single-blinded, randomized controlled trial,” in British Journal of Surgery, May 2021, vol. 108, no. Supplement 4. doi: 10.1093/bjs/znab202.015.
GLOOR, S., M. MISIRLIC, C. FREI-LANTER, P. HERZOG, P. MÜLLER, J. SCHÄFLI-THURNHERR, D. SCHREGEL, T. LAMDARK, R. WYSS, I. UNGER, D. GISI, N. GRECO, G. MUNGO, M. WIRZ, D.A. RAPTIS, C. TSCHUOR und S. BREITENSTEIN, 2021. Prehabilitation in patients undergoing colorectal surgery fails to confer reduction in overall morbidity : results of a single-center, single-blinded, randomized controlled trial. In: British Journal of Surgery [online]. Conference presentation. Oxford University Press. Mai 2021. Verfügbar unter: https://academic.oup.com/bjs/article/108/Supplement_4/znab202.015/6287411
Gloor, S., M. Misirlic, C. Frei-Lanter, P. Herzog, P. Müller, J. Schäfli-Thurnherr, D. Schregel, et al. 2021. “Prehabilitation in Patients Undergoing Colorectal Surgery Fails to Confer Reduction in Overall Morbidity : Results of a Single-Center, Single-Blinded, Randomized Controlled Trial.” Conference presentation. In British Journal of Surgery. Vol. 108. Oxford University Press. https://doi.org/10.1093/bjs/znab202.015.
Gloor, S., et al. “Prehabilitation in Patients Undergoing Colorectal Surgery Fails to Confer Reduction in Overall Morbidity : Results of a Single-Center, Single-Blinded, Randomized Controlled Trial.” British Journal of Surgery, vol. 108, no. Supplement 4, Oxford University Press, 2021, https://doi.org/10.1093/bjs/znab202.015.
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