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https://doi.org/10.21256/zhaw-21944| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes |
| Autor/-in: | Schirmer, Cedric Maschke, Rüdiger Pörtner, Ralf Eibl, Dieter |
| et. al: | No |
| DOI: | 10.1007/s00253-021-11180-7 10.21256/zhaw-21944 |
| Erschienen in: | Applied Microbiology and Biotechnology |
| Erscheinungsdatum: | 2-Mär-2021 |
| Verlag / Hrsg. Institution: | Springer |
| ISSN: | 0175-7598 1432-0614 |
| Sprache: | Englisch |
| Schlagwörter: | Bioreactor agitation; Magnetic coupling; Mechanical sealing; Lip seal; Hygienic requirements; Application trends |
| Fachgebiet (DDC): | 660: Technische Chemie |
| Zusammenfassung: | No matter the scale, stirred tank bioreactors are the most commonly used systems in biotechnological production processes. Single-use and reusable systems are supplied by several manufacturers. The type, size, and number of impellers used in these systems have a significant influence on the characteristics and designs of bioreactors. Depending on the desired application, classic shaft-driven systems, bearing-mounted drives, or stirring elements that levitate freely in the vessel may be employed. In systems with drive shafts, process hygiene requirements also affect the type of seal used. For sensitive processes with high hygienic requirements, magnetic-driven stirring systems, which have been the focus of much research in recent years, are recommended. This review provides the reader with an overview of the most common agitation and seal types implemented in stirred bioreactor systems, highlights their advantages and disadvantages, and explains their possible fields of application. Special attention is paid to the development of magnetically driven agitators, which are widely used in reusable systems and are also becoming more and more important in their single-use counterparts. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/21944 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | CC BY 4.0: Namensnennung 4.0 International |
| Departement: | Life Sciences und Facility Management |
| Organisationseinheit: | Institut für Chemie und Biotechnologie (ICBT) |
| Enthalten in den Sammlungen: | Publikationen Life Sciences und Facility Management |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| 2021_Schirmer_An overview_of_drive_systems_Applied_Microbiology_and_Biotechnology.pdf | 1.22 MB | Adobe PDF |  Öffnen/Anzeigen |
Zur Langanzeige
Schirmer, C., Maschke, R., Pörtner, R., & Eibl, D. (2021). An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-021-11180-7
Schirmer, C. et al. (2021) ‘An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes’, Applied Microbiology and Biotechnology [Preprint]. Available at: https://doi.org/10.1007/s00253-021-11180-7.
C. Schirmer, R. Maschke, R. Pörtner, and D. Eibl, “An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes,” Applied Microbiology and Biotechnology, Mar. 2021, doi: 10.1007/s00253-021-11180-7.
SCHIRMER, Cedric, Rüdiger MASCHKE, Ralf PÖRTNER und Dieter EIBL, 2021. An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes. Applied Microbiology and Biotechnology. 2 März 2021. DOI 10.1007/s00253-021-11180-7
Schirmer, Cedric, Rüdiger Maschke, Ralf Pörtner, and Dieter Eibl. 2021. “An Overview of Drive Systems and Sealing Types in Stirred Bioreactors Used in Biotechnological Processes.” Applied Microbiology and Biotechnology, March. https://doi.org/10.1007/s00253-021-11180-7.
Schirmer, Cedric, et al. “An Overview of Drive Systems and Sealing Types in Stirred Bioreactors Used in Biotechnological Processes.” Applied Microbiology and Biotechnology, Mar. 2021, https://doi.org/10.1007/s00253-021-11180-7.
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