Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3962
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dc.contributor.authorMelloh, Markus-
dc.contributor.authorRöder, Christoph-
dc.contributor.authorElfering, Achim-
dc.contributor.authorTheis, Jean-Claude-
dc.contributor.authorMüller, Urs-
dc.contributor.authorStaub, Lukas P.-
dc.contributor.authorAghayev, Emin-
dc.contributor.authorZweig, Thomas-
dc.contributor.authorBarz, Thomas-
dc.contributor.authorKohlmann, Thomas-
dc.contributor.authorWieser, Simon-
dc.contributor.authorJüni, Peter-
dc.contributor.authorZwahlen, Marcel-
dc.date.accessioned2018-08-30T06:38:20Z-
dc.date.available2018-08-30T06:38:20Z-
dc.date.issued2008-
dc.identifier.issn1471-2474de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/9939-
dc.description.abstractBackground: There is little evidence on differences across health care systems in choice and outcome of the treatment of chronic low back pain (CLBP) with spinal surgery and conservative treatment as the main options. At least six randomised controlled trials comparing these two options have been performed; they show conflicting results without clear-cut evidence for superior effectiveness of any of the evaluated interventions and could not address whether treatment effect varied across patient subgroups. Cost-utility analyses display inconsistent results when comparing surgical and conservative treatment of CLBP. Due to its higher feasibility, we chose to conduct a prospective observational cohort study. Methods: This study aims to examine if 1. Differences across health care systems result in different treatment outcomes of surgical and conservative treatment of CLBP 2. Patient characteristics (work-related, psychological factors, etc.) and co-interventions (physiotherapy, cognitive behavioural therapy, return-to-work programs, etc.) modify the Outcome of treatment for CLBP 3. Cost-utility in terms of quality-adjusted life years differs between surgical and conservative treatment of CLBP. This study will recruit 1000 patients from orthopaedic spine units, rehabilitation centres, and pain clinics in Switzerland and New Zealand. Effectiveness will be measured by the Oswestry Disability Index (ODI) at baseline and after six months. The change in ODI will be the primary endpoint of this study. Multiple linear regression models will be used, with the change in ODI from baseline to six months as the dependent variable and the type of health care system, type of treatment, Patient characteristics, and co-interventions as independent variables. Interactions will be incorporated between type of treatment and different co-interventions and patient characteristics. Cost-utility will be measured with an index based on EQol-5D in combination with cost data. Conclusion: This study will provide evidence if differences across health care systems in the outcome of treatment of CLBP exist. It will classify patients with CLBP into different clinical subgroups and help to identify specific target groups who might benefit from specific surgical or conservative interventions. Furthermore, cost-utility differences will be identified for different groups of patients with CLBP. Main results of this study should be replicated in future studies on CLBP.de_CH
dc.language.isoende_CH
dc.publisherBioMed Centralde_CH
dc.relation.ispartofBMC musculoskeletal disordersde_CH
dc.rightshttp://creativecommons.org/licenses/by/2.0/de_CH
dc.subjectChronic diseasede_CH
dc.subjectDelivery of health carede_CH
dc.subjectHealth care costde_CH
dc.subjectHumande_CH
dc.subjectLow back painde_CH
dc.subjectNew Zealandde_CH
dc.subjectOutcome assessmentde_CH
dc.subjectSwitzerlandde_CH
dc.subjectCross-cultural comparisonde_CH
dc.subjectProspective studyde_CH
dc.subjectCost-utilityde_CH
dc.subjectStudy protocolde_CH
dc.subject.ddc617.5: Orthopädische Chirurgiede_CH
dc.titleDifferences across health care systems in outcome and cost-utility of surgical and conservative treatment of chronic low back pain : a study protocolde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Management and Lawde_CH
zhaw.organisationalunitWinterthurer Institut für Gesundheitsökonomie (WIG)de_CH
dc.identifier.doi10.1186/1471-2474-9-81de_CH
dc.identifier.doi10.21256/zhaw-3962de_CH
dc.identifier.pmid18534034de_CH
zhaw.funding.euNode_CH
zhaw.issue81de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume9de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in Collections:Publikationen School of Management and Law

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