Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-3684
Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate |
Authors: | Mazenauer, Manuel R. Manov, Stole Galati, Vanessa M. Kappeler, Philipp Stohner, Jürgen |
DOI: | 10.21256/zhaw-3684 10.1039/C7RA09727A |
Published in: | RSC Advances |
Volume(Issue): | 7 |
Issue: | 87 |
Page(s): | 55434 |
Pages to: | 55440 |
Issue Date: | 2017 |
Publisher / Ed. Institution: | Royal Society of Chemistry |
ISSN: | 2046-2069 |
Language: | English |
Subject (DDC): | 540: Chemistry |
Abstract: | Chiral halomethane is the smallest stable molecule with a single asymmetric C-atom and halogenated acetic acids often serve as precursors. We focus on a synthetic route to synthesise chiral halogenated acetic acids with F, Cl, Br, and H/D isotopic substitution at the α-C-atom starting from diethyl malonate. This reactant is easily available, cheap and allows the obtainment of target acids in a few reaction steps with great versatility. Among all of the possible fully halogenated acetic acids (more than one hundred, which are, in principle, accessible by this route), there are only a small number of chiral halogenated acetic acids, which have been synthesized following the devised synthetic route. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/6407 |
Fulltext version: | Published version |
License (according to publishing contract): | CC BY 3.0: Attribution 3.0 Unported |
Departement: | Life Sciences and Facility Management |
Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
Appears in collections: | Publikationen Life Sciences und Facility Management |
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Mazenauer, M. R., Manov, S., Galati, V. M., Kappeler, P., & Stohner, J. (2017). Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate. RSC Advances, 7(87), 55434–55440. https://doi.org/10.21256/zhaw-3684
Mazenauer, M.R. et al. (2017) ‘Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate’, RSC Advances, 7(87), pp. 55434–55440. Available at: https://doi.org/10.21256/zhaw-3684.
M. R. Mazenauer, S. Manov, V. M. Galati, P. Kappeler, and J. Stohner, “Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate,” RSC Advances, vol. 7, no. 87, pp. 55434–55440, 2017, doi: 10.21256/zhaw-3684.
MAZENAUER, Manuel R., Stole MANOV, Vanessa M. GALATI, Philipp KAPPELER und Jürgen STOHNER, 2017. Synthetic routes for a variety of halogenated (chiral) acetic acids from diethyl malonate. RSC Advances. 2017. Bd. 7, Nr. 87, S. 55434–55440. DOI 10.21256/zhaw-3684
Mazenauer, Manuel R., Stole Manov, Vanessa M. Galati, Philipp Kappeler, and Jürgen Stohner. 2017. “Synthetic Routes for a Variety of Halogenated (Chiral) Acetic Acids from Diethyl Malonate.” RSC Advances 7 (87): 55434–40. https://doi.org/10.21256/zhaw-3684.
Mazenauer, Manuel R., et al. “Synthetic Routes for a Variety of Halogenated (Chiral) Acetic Acids from Diethyl Malonate.” RSC Advances, vol. 7, no. 87, 2017, pp. 55434–40, https://doi.org/10.21256/zhaw-3684.
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