| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging |
| Autor/-in: | Weiss, Stephan Järmann, Thomas Schmid, Peter Staempfli, Philipp Boesiger, Peter Niederer, Peter Caduff, Rosmarie Bajka, Michael |
| DOI: | 10.1002/ar.a.20274 |
| Erschienen in: | The Anatomical Record |
| Band(Heft): | 288A |
| Heft: | 1 |
| Seite(n): | 84 |
| Seiten bis: | 90 |
| Erscheinungsdatum: | 2006 |
| Verlag / Hrsg. Institution: | Wiley |
| ISSN: | 1552-4884 1552-4892 0003-276X 1932-8494 |
| Sprache: | Englisch |
| Schlagwörter: | Adult; Anisotropy; Diffusion Magnetic Resonance Imaging; Female; Humans; Immunohistochemistry; In vitro techniques; Middle aged; Skeletal muscle fibers; Myometrium |
| Fachgebiet (DDC): | 610: Medizin und Gesundheit |
| Zusammenfassung: | The global muscle and collagen fiber orientation in the human uterus has been analyzed hitherto by various standard microscopic techniques. However, no widely accepted model of the fiber architecture of the myometrium could be acquired. The purpose of the present study was to investigate the uterus by magnetic resonance (MR) diffusion tensor imaging (DTI) in a 3D macroscopic approach. Ex vivo MR DTI measurements were performed on five uteri from nonpregnant patients. The main diffusion directions reflecting the orientation of directional structures in the examined tissues were determined from diffusion-weighted spin-echo measurements. A fiber tracking algorithm was used to extrapolate the fiber architecture. The method was validated against histological slides and indirectly through the analysis of leiomyomas, which exhibit less anisotropy than normal myometrium. Significant anisotropy was found in most regions of all examined nonpregnant human uteri. But only two systems of fibers were found running circularly along the intramural part of the uterine tubes. They merged caudally and built a close fitting envelope of circular layers around the uterine cavity. On the cervix, circular fibers were observed in the outer part as well as mostly longitudinal fibers in the inner part. These results confirm the existence of directional structures in the complex fiber architecture of the human uterus. They also indicate that MR DTI is a beneficial and complementary tool to standard microscopic techniques to determine the intrinsic fiber architecture in human organs. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/5026 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | School of Engineering |
| Enthalten in den Sammlungen: | Publikationen School of Engineering |
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Weiss, S., Järmann, T., Schmid, P., Staempfli, P., Boesiger, P., Niederer, P., Caduff, R., & Bajka, M. (2006). Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging. The Anatomical Record, 288A(1), 84–90. https://doi.org/10.1002/ar.a.20274
Weiss, S. et al. (2006) ‘Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging’, The Anatomical Record, 288A(1), pp. 84–90. Available at: https://doi.org/10.1002/ar.a.20274.
S. Weiss et al., “Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging,” The Anatomical Record, vol. 288A, no. 1, pp. 84–90, 2006, doi: 10.1002/ar.a.20274.
WEISS, Stephan, Thomas JÄRMANN, Peter SCHMID, Philipp STAEMPFLI, Peter BOESIGER, Peter NIEDERER, Rosmarie CADUFF und Michael BAJKA, 2006. Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging. The Anatomical Record. 2006. Bd. 288A, Nr. 1, S. 84–90. DOI 10.1002/ar.a.20274
Weiss, Stephan, Thomas Järmann, Peter Schmid, Philipp Staempfli, Peter Boesiger, Peter Niederer, Rosmarie Caduff, and Michael Bajka. 2006. “Three-Dimensional Fiber Architecture of the Nonpregnant Human Uterus Determined Ex Vivo Using Magnetic Resonance Diffusion Tensor Imaging.” The Anatomical Record 288A (1): 84–90. https://doi.org/10.1002/ar.a.20274.
Weiss, Stephan, et al. “Three-Dimensional Fiber Architecture of the Nonpregnant Human Uterus Determined Ex Vivo Using Magnetic Resonance Diffusion Tensor Imaging.” The Anatomical Record, vol. 288A, no. 1, 2006, pp. 84–90, https://doi.org/10.1002/ar.a.20274.
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