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dc.contributor.authorSummers, Paul-
dc.contributor.authorStämpfli, Philipp-
dc.contributor.authorJärmann, Thomas-
dc.contributor.authorKwiecinski, S.-
dc.contributor.authorKollias, S.-
dc.date.accessioned2018-04-10T14:12:59Z-
dc.date.available2018-04-10T14:12:59Z-
dc.date.issued2006-10-
dc.identifier.issn0195-6108de_CH
dc.identifier.issn1936-959Xde_CH
dc.identifier.issn1936-959Xde_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/4997-
dc.description.abstractBackground and Purpose: Diffusion tensor and diffusion-weighted spinal cord imaging remain relatively unexplored techniques despite demonstrations that such images can be obtained and may yield clinically relevant findings. In this study, we examined the temporal dynamics of spinal cord motion and their impact on diffusion tensor image quality. Methods: Four healthy volunteers underwent phase contrast-based velocity mapping and segmented echo-planar diffusion tensor scans of the cervical spinal cord. Regions of interest in the cord were used to identify the temporal patterns of motion. The delay of data acquisition after the cardiac trigger was varied to correspond to either quiescence or motion of the cord. Results: The cervical spinal cord consistently displayed maximal velocities in the range of 0.5 cm/s and accelerations of up to 25 cm/s2. In both these respects, the cervical cord values were greater than those of the medulla. Despite this pronounced motion, approximately 40% of the cardiac cycle can be described as relatively calm, with absolute velocities and accelerations less than 20% of the maximum values. Confining image acquisition to this window reduced ghosting artifacts and increased the consistency with which the dominant direction of diffusion was along the rostral-caudal axis in both gray and white matter of the spine. Preliminary clinical application and fiber tracking in pathologic cases was feasible, and alterations of the diffusion properties by multiple sclerosis lesions, tumor, and syringomyelia were seen. Conclusions: Acquiring DTI data during the quiescent phase of spinal cord motion can reduce ghosting artifacts and improve fiber tracking.de_CH
dc.language.isoende_CH
dc.publisherAmerican Society of Neuroradiologyde_CH
dc.relation.ispartofAmerican Journal of Neuroradiologyde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subject.ddc616.8: Neurologie und Krankheiten des Nervensystemsde_CH
dc.titleA preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cordde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.funding.euNode_CH
zhaw.issue9de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end1961de_CH
zhaw.pages.start1952de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume27de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
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Summers, P., Stämpfli, P., Järmann, T., Kwiecinski, S., & Kollias, S. (2006). A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord. American Journal of Neuroradiology, 27(9), 1952–1961.
Summers, P. et al. (2006) ‘A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord’, American Journal of Neuroradiology, 27(9), pp. 1952–1961.
P. Summers, P. Stämpfli, T. Järmann, S. Kwiecinski, and S. Kollias, “A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord,” American Journal of Neuroradiology, vol. 27, no. 9, pp. 1952–1961, Oct. 2006.
SUMMERS, Paul, Philipp STÄMPFLI, Thomas JÄRMANN, S. KWIECINSKI und S. KOLLIAS, 2006. A preliminary study of the effects of trigger timing on diffusion tensor imaging of the human spinal cord. American Journal of Neuroradiology. Oktober 2006. Bd. 27, Nr. 9, S. 1952–1961
Summers, Paul, Philipp Stämpfli, Thomas Järmann, S. Kwiecinski, and S. Kollias. 2006. “A Preliminary Study of the Effects of Trigger Timing on Diffusion Tensor Imaging of the Human Spinal Cord.” American Journal of Neuroradiology 27 (9): 1952–61.
Summers, Paul, et al. “A Preliminary Study of the Effects of Trigger Timing on Diffusion Tensor Imaging of the Human Spinal Cord.” American Journal of Neuroradiology, vol. 27, no. 9, Oct. 2006, pp. 1952–61.


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