Publikationstyp: Beitrag in wissenschaftlicher Zeitschrift
Art der Begutachtung: Peer review (Publikation)
Titel: Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children : importance of gender and associations with behavioral/emotional difficulties
Autor/-in: Hatzinger, Martin
Brand, Serge
Perren, Sonja
von Wyl, Agnes
von Klitzing, Kai
Holsboer-Trachsler, Edith
DOI: 10.1016/j.jpsychires.2006.07.012
Erschienen in: Journal of Psychiatric Research
Band(Heft): 41
Heft: 10
Seite(n): 861
Seiten bis: 870
Erscheinungsdatum: Nov-2007
Verlag / Hrsg. Institution: Elsevier
ISSN: 0022-3956
1879-1379
Sprache: Englisch
Schlagwörter: Child; HPA system; Prediction; Gender
Fachgebiet (DDC): 155: Differentielle Psychologie und Entwicklungspsychologie
616.8: Neurologie und Krankheiten des Nervensystems
618.92: Pädiatrie
Zusammenfassung: The current cross-sectional study investigated basal and stress-challenged hypothalamic-pituitary-adrenocortical (HPA) system function in 102 five-year old kindergarten children (59 boys, 43 girls) who had been assessed by a comprehensive psychological and behavioral test battery. Baseline HPA system activity was significantly increased in girls when compared to boys (p < 0.001). Furthermore, basal HPA system activity predicted a high hormonal release during stress with – again – girls showing higher hormonal responses than boys (p < 0.01). Importantly, increased HPA system activity (baseline and stress-challenged) was significantly associated with hyperactivity/impulsivity and emotional problems in boys and with positive emotions in girls (p < 0.05). These results suggest an occurrence of neurobiological alterations early in development. The observed neurobiological changes are gender specific already at the age of 5 years. Prospective long-term follow up of the identified subjects with HPA axis alterations will clarify if these markers are predictive for the onset of psychiatric disorders.
URI: https://digitalcollection.zhaw.ch/handle/11475/3991
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): Lizenz gemäss Verlagsvertrag
Departement: Angewandte Psychologie
Organisationseinheit: Psychologisches Institut (PI)
Enthalten in den Sammlungen:Publikationen Angewandte Psychologie

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Hatzinger, M., Brand, S., Perren, S., von Wyl, A., von Klitzing, K., & Holsboer-Trachsler, E. (2007). Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children : importance of gender and associations with behavioral/emotional difficulties. Journal of Psychiatric Research, 41(10), 861–870. https://doi.org/10.1016/j.jpsychires.2006.07.012
Hatzinger, M. et al. (2007) ‘Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children : importance of gender and associations with behavioral/emotional difficulties’, Journal of Psychiatric Research, 41(10), pp. 861–870. Available at: https://doi.org/10.1016/j.jpsychires.2006.07.012.
M. Hatzinger, S. Brand, S. Perren, A. von Wyl, K. von Klitzing, and E. Holsboer-Trachsler, “Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children : importance of gender and associations with behavioral/emotional difficulties,” Journal of Psychiatric Research, vol. 41, no. 10, pp. 861–870, Nov. 2007, doi: 10.1016/j.jpsychires.2006.07.012.
HATZINGER, Martin, Serge BRAND, Sonja PERREN, Agnes VON WYL, Kai VON KLITZING und Edith HOLSBOER-TRACHSLER, 2007. Hypothalamic-pituitary-adrenocortical (HPA) activity in kindergarten children : importance of gender and associations with behavioral/emotional difficulties. Journal of Psychiatric Research. November 2007. Bd. 41, Nr. 10, S. 861–870. DOI 10.1016/j.jpsychires.2006.07.012
Hatzinger, Martin, Serge Brand, Sonja Perren, Agnes von Wyl, Kai von Klitzing, and Edith Holsboer-Trachsler. 2007. “Hypothalamic-Pituitary-Adrenocortical (HPA) Activity in Kindergarten Children : Importance of Gender and Associations with Behavioral/Emotional Difficulties.” Journal of Psychiatric Research 41 (10): 861–70. https://doi.org/10.1016/j.jpsychires.2006.07.012.
Hatzinger, Martin, et al. “Hypothalamic-Pituitary-Adrenocortical (HPA) Activity in Kindergarten Children : Importance of Gender and Associations with Behavioral/Emotional Difficulties.” Journal of Psychiatric Research, vol. 41, no. 10, Nov. 2007, pp. 861–70, https://doi.org/10.1016/j.jpsychires.2006.07.012.


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