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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1754
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dc.contributor.authorBono, Epifania-
dc.contributor.authorMathes, Stephanie H-
dc.contributor.authorFranscini, Nicola-
dc.contributor.authorGraf-Hausner, Ursula-
dc.date.accessioned2018-02-28T12:03:29Z-
dc.date.available2018-02-28T12:03:29Z-
dc.date.issued2010-11-
dc.identifier.issn0009-4293de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/3295-
dc.description.abstractTissue Engineering as an emerging biotechnology sector aims at the in vitro regeneration of diseased tissues and promises to profoundly change medical practice, offering the possibility of regenerating tissues and organs instead of just repairing them (regenerative medicine). Improved healing processes and a higher quality of life are the expected results. This article gives an overview of different technologies for regenerative medicine and presents results of our own current applied research and development. A recent project was successfully closed with the development of a natural biomaterial for soft tissue oral defects. The establishment of an in vitro bioreactor system enabled us to simulate the mechanical and biological environment in a healing wound and to investigate the suitability of different implant materials for the oral tissue regeneration. Moreover, focusing the attention on an alternative method for the intervertebral disc (IVD) regeneration, we established a new tissue engineered approach, based on the three-dimensional (3D) culture of autologous human IVD cells into a polyurethane (PU)-fibrin composite. IVD cells were able to proliferate and, thanks to the 3D conditions, to differentiate expressing the typical native tissue markers. The development of an automated platform was the goal of an additional project, to standardize the cell culture technology, increase the bio-safety and reduce the production costs, moving tissue engineering nearer to clinical application.de_CH
dc.language.isoende_CH
dc.publisherSchweizerische Chemische Gesellschaftde_CH
dc.relation.ispartofChimiade_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectIcbcde_CH
dc.subjectAutomationde_CH
dc.subjectBiomaterialsde_CH
dc.subjectDisc regenerationde_CH
dc.subjectSoft tissuede_CH
dc.subjectTissue regenerationde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleTissue Engineering - the gateway to regenerative medicinede_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.publisher.placeBernde_CH
dc.identifier.doi10.21256/zhaw-1754-
dc.identifier.doi10.2533/chimia.2010.808de_CH
zhaw.funding.euNode_CH
zhaw.issue11de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end812de_CH
zhaw.pages.start808de_CH
zhaw.parentwork.editorAlexakis, Domenico P.-
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume64de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
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Bono, E., Mathes, S. H., Franscini, N., & Graf-Hausner, U. (2010). Tissue Engineering - the gateway to regenerative medicine. Chimia, 64(11), 808–812. https://doi.org/10.21256/zhaw-1754
Bono, E. et al. (2010) ‘Tissue Engineering - the gateway to regenerative medicine’, Chimia. Edited by D.P. Alexakis, 64(11), pp. 808–812. Available at: https://doi.org/10.21256/zhaw-1754.
E. Bono, S. H. Mathes, N. Franscini, and U. Graf-Hausner, “Tissue Engineering - the gateway to regenerative medicine,” Chimia, vol. 64, no. 11, pp. 808–812, Nov. 2010, doi: 10.21256/zhaw-1754.
BONO, Epifania, Stephanie H MATHES, Nicola FRANSCINI und Ursula GRAF-HAUSNER, 2010. Tissue Engineering - the gateway to regenerative medicine. Domenico P. ALEXAKIS (Hrsg.), Chimia. November 2010. Bd. 64, Nr. 11, S. 808–812. DOI 10.21256/zhaw-1754
Bono, Epifania, Stephanie H Mathes, Nicola Franscini, and Ursula Graf-Hausner. 2010. “Tissue Engineering - the Gateway to Regenerative Medicine.” Edited by Domenico P. Alexakis. Chimia 64 (11): 808–12. https://doi.org/10.21256/zhaw-1754.
Bono, Epifania, et al. “Tissue Engineering - the Gateway to Regenerative Medicine.” Chimia, edited by Domenico P. Alexakis, vol. 64, no. 11, Nov. 2010, pp. 808–12, https://doi.org/10.21256/zhaw-1754.


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