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Title: Cell-seeded thermoreversible hydrogel-polyurethane composites for nucleus pulposus augmentation
Authors : Striegl, Britta
Grad, S.
Eglin, D
Benneker, L.
Peroglio, M.
Alini, M.
Graf-Hausner, Ursula
Bono, Epifania
Proceedings: Proceedings of the 3D Cell Culture 2012 congress
Conference details: 3D Cell Culture 2012, Zurich, March 14-16, 2012
Publisher / Ed. Institution : Dechema Biotechnologie
Issue Date: 2012
License (according to publishing contract) : Licence according to publishing contract
Type of review: Not specified
Language : English
Subject (DDC) : 610: Medicine and health
Abstract: Tissue engineering represents an alternative approach to the current invasive surgical procedures for the intervertebral disc (IVD) repair. The combination of injectable hydrogels and elastic biomaterials allow three-dimensional cell cultures and provide mechanical stability. In the present study a thermoreversible hyaluronan (HA) hydrogel as well as fibrin glue were mixed with polyurethane (PU) and their effect was investigated on the proliferation and differentiation of human IVD (hIVD cells) and mesenchymal stem cells (hMSCs) by in vitro and ex-vivo experiments.
Departement: Life Sciences und Facility Management
Publication type: Conference Poster
DOI : 10.21256/zhaw-1752
Appears in Collections:Publikationen Life Sciences und Facility Management

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