Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Thermal cleavage of the Fmoc protection group |
Authors: | Höck, Stefan Marti, Roger Riedl, Rainer Simeunovic, Marina |
DOI: | 10.2533/chimia.2010.200 |
Published in: | Chimia |
Volume(Issue): | 64 |
Issue: | 3 |
Page(s): | 200 |
Pages to: | 202 |
Issue Date: | Mar-2010 |
Publisher / Ed. Institution: | Schweizerische Chemische Gesellschaft |
ISSN: | 0009-4293 |
Language: | English |
Subjects: | Peptide synthesis; Dibenzofulvene; High-temperature NMR; Fmoc protection group |
Subject (DDC): | 540: Chemistry |
Abstract: | The Fmoc protection group is among the most commonly used protection groups for the amino function. A fast method for the thermal deavage of this protection group under base-free conditions without the need for dibenzofulvene scavengers is presented. The advantages of this method include straightforward testability by means of a simple high-temperature NMR experiment, usually high yields, and good selectivity towards the BOC protection group and t-butyl ethers. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/2759 |
Fulltext version: | Published version |
License (according to publishing contract): | Licence according to publishing contract |
Departement: | Life Sciences and Facility Management |
Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
Appears in collections: | Publikationen Life Sciences und Facility Management |
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Höck, S., Marti, R., Riedl, R., & Simeunovic, M. (2010). Thermal cleavage of the Fmoc protection group. Chimia, 64(3), 200–202. https://doi.org/10.2533/chimia.2010.200
Höck, S. et al. (2010) ‘Thermal cleavage of the Fmoc protection group’, Chimia, 64(3), pp. 200–202. Available at: https://doi.org/10.2533/chimia.2010.200.
S. Höck, R. Marti, R. Riedl, and M. Simeunovic, “Thermal cleavage of the Fmoc protection group,” Chimia, vol. 64, no. 3, pp. 200–202, Mar. 2010, doi: 10.2533/chimia.2010.200.
HÖCK, Stefan, Roger MARTI, Rainer RIEDL und Marina SIMEUNOVIC, 2010. Thermal cleavage of the Fmoc protection group. Chimia. März 2010. Bd. 64, Nr. 3, S. 200–202. DOI 10.2533/chimia.2010.200
Höck, Stefan, Roger Marti, Rainer Riedl, and Marina Simeunovic. 2010. “Thermal Cleavage of the Fmoc Protection Group.” Chimia 64 (3): 200–202. https://doi.org/10.2533/chimia.2010.200.
Höck, Stefan, et al. “Thermal Cleavage of the Fmoc Protection Group.” Chimia, vol. 64, no. 3, Mar. 2010, pp. 200–2, https://doi.org/10.2533/chimia.2010.200.
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