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https://doi.org/10.21256/zhaw-26920| Publication type: | Article in scientific journal |
| Type of review: | Not specified |
| Title: | Of balls, inks and cages : hybrid biofabrication of 3D tissue analogs |
| Authors: | Moldovan, Nicanor I. Moldovan, Leni Raghunath, Michael |
| et. al: | No |
| DOI: | 10.18063/ijb.v5i1.167 10.21256/zhaw-26920 |
| Published in: | International Journal of Bioprinting |
| Volume(Issue): | 5 |
| Issue: | 1 |
| Page(s): | 167 |
| Issue Date: | 2019 |
| Publisher / Ed. Institution: | Whioce |
| ISSN: | 2424-8002 2424-7723 |
| Language: | English |
| Subjects: | Tissue engineering; Bioprinting; Scaffold-free; Scaffolds |
| Subject (DDC): | 610.28: Biomedicine, biomedical engineering |
| Abstract: | The overarching principle of three-dimensional (3D) bioprinting is the placing of cells or cell clusters in the 3D space to generate a cohesive tissue microarchitecture that comes close to in vivo characteristics. To achieve this goal, several technical solutions are available, generating considerable combinatorial bandwidth: (i) Support structures are generated first, and cells are seeded subsequently; (ii) alternatively, cells are delivered in a printing medium, so-called "bioink," that contains them during the printing process and ensures shape fidelity of the generated structure; and (iii) a "scaffold-free" version of bioprinting, where only cells are used and the extracellular matrix is produced by the cells themselves, also recently entered a phase of accelerated development and successful applications. However, the scaffold-free approaches may still benefit from secondary incorporation of scaffolding materials, thus expanding their versatility. Reversibly, the bioink-based bioprinting could also be improved by adopting some of the principles and practices of scaffold-free biofabrication. Collectively, we anticipate that combinations of these complementary methods in a "hybrid" approach, rather than their development in separate technological niches, will largely increase their efficiency and applicability in tissue engineering. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/26920 |
| Fulltext version: | Published version |
| License (according to publishing contract): | CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International |
| Departement: | Life Sciences and Facility Management |
| Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
| Appears in collections: | Publikationen Life Sciences und Facility Management |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 2019_Moldovan-etal_Of-balls-inks-and-cages_InternationalJBioprinting.pdf | 514.27 kB | Adobe PDF |  View/Open |
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Moldovan, N. I., Moldovan, L., & Raghunath, M. (2019). Of balls, inks and cages : hybrid biofabrication of 3D tissue analogs. International Journal of Bioprinting, 5(1), 167. https://doi.org/10.18063/ijb.v5i1.167
Moldovan, N.I., Moldovan, L. and Raghunath, M. (2019) ‘Of balls, inks and cages : hybrid biofabrication of 3D tissue analogs’, International Journal of Bioprinting, 5(1), p. 167. Available at: https://doi.org/10.18063/ijb.v5i1.167.
N. I. Moldovan, L. Moldovan, and M. Raghunath, “Of balls, inks and cages : hybrid biofabrication of 3D tissue analogs,” International Journal of Bioprinting, vol. 5, no. 1, p. 167, 2019, doi: 10.18063/ijb.v5i1.167.
MOLDOVAN, Nicanor I., Leni MOLDOVAN und Michael RAGHUNATH, 2019. Of balls, inks and cages : hybrid biofabrication of 3D tissue analogs. International Journal of Bioprinting. 2019. Bd. 5, Nr. 1, S. 167. DOI 10.18063/ijb.v5i1.167
Moldovan, Nicanor I., Leni Moldovan, and Michael Raghunath. 2019. “Of Balls, Inks and Cages : Hybrid Biofabrication of 3D Tissue Analogs.” International Journal of Bioprinting 5 (1): 167. https://doi.org/10.18063/ijb.v5i1.167.
Moldovan, Nicanor I., et al. “Of Balls, Inks and Cages : Hybrid Biofabrication of 3D Tissue Analogs.” International Journal of Bioprinting, vol. 5, no. 1, 2019, p. 167, https://doi.org/10.18063/ijb.v5i1.167.
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