Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data

Grobet, Cécile; Audigé, Laurent; Eichler, Klaus; Meier, Flurina; Marks, Miriam; Herren, Daniel B.

doi:10.1016/j.jhsa.2022.01.013

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-25365

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data
Authors:	Grobet, Cécile Audigé, Laurent Eichler, Klaus Meier, Flurina Marks, Miriam Herren, Daniel B.
et. al:	No
DOI:	10.1016/j.jhsa.2022.01.013 10.21256/zhaw-25365
Published in:	Journal of Hand Surgery (American Volume)
Volume(Issue):	47
Issue:	5
Page(s):	445
Pages to:	453
Issue Date:	2022
Publisher / Ed. Institution:	Elsevier
ISSN:	0363-5023 1531-6564
Language:	English
Subjects:	Cost-effectiveness; Cost-utility; Quality of life; Thumb carpometacarpal osteoarthritis
Subject (DDC):	362.1041: Health economics 617.5: Orthopaedic surgery
Abstract:	Purpose: Knowledge about the costs and benefits of hand surgical interventions is important for surgeons, payers, and policy makers. Little is known about the cost-effectiveness of surgery for thumb carpometacarpal osteoarthritis. The objective of this study was to examine patients’ quality of life and economic costs, with focus on the cost-utility ratio 1 year after surgery for thumb carpometacarpal osteoarthritis compared with that for continued nonsurgical management. Methods: Patients with thumb carpometacarpal osteoarthritis indicated for resection arthroplasty were included in a prospective study. The quality of life (using European Quality of Life-5 Dimensions-5 Level), direct medical costs, and productivity losses were assessed up to 1 year after surgery. Baseline data at recruitment and costs sustained over 1 year before surgery served as a proxy for nonsurgical management. The total costs to gain 1 extra quality-adjusted life year and the incremental cost-effectiveness ratio were calculated from a health care system and a societal perspective. Results: The mean European Quality of Life-5 Dimensions-5 Level value for 151 included patients improved significantly from 0.69 to 0.88 (after surgery). The productivity loss during the preoperative period was 47% for 49 working patients, which decreased to 26% 1 year after surgery. The total costs increased from US $20,451 in the preoperative year to US $24,374 in the postoperative year. This resulted in an incremental cost-effectiveness ratio of US $25,370 per quality-adjusted life year for surgery compared with that for simulated nonsurgical management. Conclusions: The calculated incremental cost-effectiveness ratio was clearly below the suggested Swiss threshold of US $92,000, indicating that thumb carpometacarpal surgery is a cost-effective intervention.
URI:	https://digitalcollection.zhaw.ch/handle/11475/25365
Fulltext version:	Accepted version
License (according to publishing contract):	CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Restricted until:	2023-05-01
Departement:	School of Management and Law
Organisational Unit:	Winterthur Institute of Health Economics (WIG)
Appears in collections:	Publikationen School of Management and Law

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Grobet, C., Audigé, L., Eichler, K., Meier, F., Marks, M., & Herren, D. B. (2022). Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data. Journal of Hand Surgery (American Volume), 47(5), 445–453. https://doi.org/10.1016/j.jhsa.2022.01.013

Grobet, C. et al. (2022) ‘Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data’, Journal of Hand Surgery (American Volume), 47(5), pp. 445–453. Available at: https://doi.org/10.1016/j.jhsa.2022.01.013.

C. Grobet, L. Audigé, K. Eichler, F. Meier, M. Marks, and D. B. Herren, “Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data,” Journal of Hand Surgery (American Volume), vol. 47, no. 5, pp. 445–453, 2022, doi: 10.1016/j.jhsa.2022.01.013.

GROBET, Cécile, Laurent AUDIGÉ, Klaus EICHLER, Flurina MEIER, Miriam MARKS und Daniel B. HERREN, 2022. Cost-utility analysis of thumb carpometacarpal resection arthroplasty : a health economic study using real-world data. Journal of Hand Surgery (American Volume). 2022. Bd. 47, Nr. 5, S. 445–453. DOI 10.1016/j.jhsa.2022.01.013

Grobet, Cécile, Laurent Audigé, Klaus Eichler, Flurina Meier, Miriam Marks, and Daniel B. Herren. 2022. “Cost-Utility Analysis of Thumb Carpometacarpal Resection Arthroplasty : A Health Economic Study Using Real-World Data.” Journal of Hand Surgery (American Volume) 47 (5): 445–53. https://doi.org/10.1016/j.jhsa.2022.01.013.

Grobet, Cécile, et al. “Cost-Utility Analysis of Thumb Carpometacarpal Resection Arthroplasty : A Health Economic Study Using Real-World Data.” Journal of Hand Surgery (American Volume), vol. 47, no. 5, 2022, pp. 445–53, https://doi.org/10.1016/j.jhsa.2022.01.013.