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Title: Design of bioreactors suitable for plant cell and tissue cultures
Authors : Eibl-Schindler, Regine
Eibl, Dieter
Published in : Phytochemistry Reviews
Volume(Issue) : 7
Issue : 3
Pages : 593
Pages to: 598
Publisher / Ed. Institution : Springer
Publisher / Ed. Institution: Berlin
Issue Date: 22-Dec-2007
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (publication)
Language : English
Subjects : Disposable bioreactors; Hairy roots; Plant cell suspension cultures; Secondary metabolites and recombinant proteins; Traditional bioreactors
Subject (DDC) : 660: Chemical engineering
Abstract: Plant cell suspension cultures and hairy roots are potential sources of secondary metabolites and recombinant proteins. In contrast to traditionally grown “whole wild plants” or “whole transgenic plants”, their production in bioreactors guarantees defined controlled process conditions and therefore minimizes or even prevents variations in product yield and quality, which simplifies process validation and product registration. Moreover, bioreactors and their configuration significantly affect cultivation results by accomplishing and controlling the optimum environment for effective cell growth and production of bioactive substances. This review highlights the main design criteria of the most widely used bioreactor types, both for plant cell suspension cultures and for hairy roots, and outlines suitable low-cost disposable bioreactors which have found increasing acceptance over the last 10 years.
Further description : Erworben im Rahmen der Schweizer Nationallizenzen (
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Publication type: Article in scientific journal
DOI : 10.21256/zhaw-1589
ISSN: 1568-7767
Appears in Collections:Publikationen Life Sciences und Facility Management

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