Title: Association between processing speed and subclinical psychotic symptoms in the general population : focusing on sex differences
Authors : Rössler, Wulf
Ajdacic-Gross, Vladeta
Müller, Mario
Rodgers, Stephanie
Kawohl, Wolfram
Haker, Helene
Hengartner, Michael Pascal
Published in : Schizophrenia Research
Volume(Issue) : 166
Issue : 1-3
Pages : 316
Pages to: 321
Publisher / Ed. Institution : Elsevier BV
Issue Date: Aug-2015
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Publication)
Language : English
Subjects : Subclinical psychosis; Psychotic-like experiences; Schizotypy; Schizophrenia spectrum; Cognitive deficits; Processing speed; Sex differences
Subject (DDC) : 305: Social groups
616.89: Mental disorders, clinical psychology and psychiatry
Abstract: Evidence is growing that persons along the schizophrenia spectrum, i.e., those who also display subclinical psychotic symptoms, exhibit deficits across a broad range of neuropsychological domains. Because sex differences in the association between cognitive deficits and psychosis have thus far been mostly neglected, we believe that ours is the first study specifically focused upon those differences when examining the relationship between subclinical psychosis and processing speed. Using a sample of 213 persons from the general population from Zurich, Switzerland, psychotic symptoms were assessed with three different questionnaires including the Schizotypal Personality Questionnaire, an adaptation of the Structured Interview for Assessing Perceptual Anomalies, and the Paranoia Checklist. Processing speed was assessed with the WAIS digit-symbol coding test. Two higher-order psychosis domains were factor-analytically derived from the various psychosis subscales and then subjected to a series of linear regression analyses. The results demonstrate that in both men and women associations between subclinical psychosis domains and processing speed were weak to moderate (β ranging from − 0.18 to − 0.27; all p < 0.05). However, we found no sex-differences in the interrelation of subclinical psychosis and processing speed (ΔR2 < 0.005; p > 0.30). In conclusion, it appears that sex differences in psychosis manifest themselves only at the high end of the continuum (full-blown schizophrenia) and not across the sub-threshold range. The small magnitude of the effects reported herein conforms to the etiopathology of the disorder. Since schizophrenia and related disorders from the spectrum are assumed to be multifactorial diseases, it follows that many etiological components of small effect are involved.
Departement: Applied Psychology
Organisational Unit: Psychological Institute (PI)
Publication type: Article in scientific Journal
DOI : 10.1016/j.schres.2015.05.026
ISSN: 0920-9964
URI: https://digitalcollection.zhaw.ch/handle/11475/2285
Appears in Collections:Publikationen Angewandte Psychologie

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