| Publication type: | Book part |
| Type of review: | Editorial review |
| Title: | Bag bioreactor based on wave-induced motion : characteristics and applications |
| Authors: | Eibl-Schindler, Regine Werner, Sören Eibl, Dieter |
| DOI: | 10.1007/10_2008_15 |
| Published in: | Disposable Bioreactors |
| Editors of the parent work: | Eibl-Schindler, Regine Eibl, Dieter |
| Page(s): | 55 |
| Pages to: | 87 |
| Issue Date: | 2010 |
| Series: | Advances in Biochemical Engineering / Biotechnology |
| Series volume: | 115 |
| Publisher / Ed. Institution: | Springer |
| Publisher / Ed. Institution: | Berlin |
| ISBN: | 978-3-642-01871-8 978-3-642-01872-5 |
| Language: | English |
| Subjects: | Animal cells; Biological insecticides; Biotransformation; Immunomodulator; Plant cells; Seed inoculum; Wave-mixed bag bioreactor |
| Subject (DDC): | 660: Chemical engineering |
| Abstract: | Today wave-mixed bag bioreactors are common devices in modern biotechnological processes where simple, safe and flexible production has top priority. Numerous studies that have been published on ex vivo generation of cells, viruses and therapeutic agents during the last 10 years have confirmed their suitability and even superiority to stirred bioreactors made from glass or stainless steel for animal as well as plant cell cultivations. In these studies the wave-mixed bag bioreactors enabled middle to high cell density and adequate productivity in laboratory and pilot scale. This mainly results from low-shear conditions and highly efficient oxygen transfer for cell cultures, as demonstrated for the widely used BioWave®. Starting with an overview of wave-mixed bag bioreactors and their common operation strategies, this chapter delineates engineering aspects of BioWave®, which like Wave Reactor™ and BIOSTAT®CultiBag RM originates from the prototype of a wave-mixed bag bioreactor introduced in 1998. Subsequently, the second part of the chapter focuses on reported BioWave® applications. Conditions and results from cultivations with animal cells, plant cells, microbial cells and nematodes are presented and discussed. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2266 |
| Fulltext version: | Published version |
| License (according to publishing contract): | Licence according to publishing contract |
| Departement: | Life Sciences and Facility Management |
| Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
| Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
There are no files associated with this item.
Show full item record
Eibl-Schindler, R., Werner, S., & Eibl, D. (2010). Bag bioreactor based on wave-induced motion : characteristics and applications. In R. Eibl-Schindler & D. Eibl (Eds.), Disposable Bioreactors (pp. 55–87). Springer. https://doi.org/10.1007/10_2008_15
Eibl-Schindler, R., Werner, S. and Eibl, D. (2010) ‘Bag bioreactor based on wave-induced motion : characteristics and applications’, in R. Eibl-Schindler and D. Eibl (eds) Disposable Bioreactors. Berlin: Springer, pp. 55–87. Available at: https://doi.org/10.1007/10_2008_15.
R. Eibl-Schindler, S. Werner, and D. Eibl, “Bag bioreactor based on wave-induced motion : characteristics and applications,” in Disposable Bioreactors, R. Eibl-Schindler and D. Eibl, Eds. Berlin: Springer, 2010, pp. 55–87. doi: 10.1007/10_2008_15.
EIBL-SCHINDLER, Regine, Sören WERNER und Dieter EIBL, 2010. Bag bioreactor based on wave-induced motion : characteristics and applications. In: Regine EIBL-SCHINDLER und Dieter EIBL (Hrsg.), Disposable Bioreactors. Berlin: Springer. S. 55–87. ISBN 978-3-642-01871-8
Eibl-Schindler, Regine, Sören Werner, and Dieter Eibl. 2010. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” In Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, 55–87. Berlin: Springer. https://doi.org/10.1007/10_2008_15.
Eibl-Schindler, Regine, et al. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, Springer, 2010, pp. 55–87, https://doi.org/10.1007/10_2008_15.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.