Development of the travelling wave bioreactor. Part I : design studies based on numerical models

Kaiser, Stephan; Kraume, Matthias; Eibl, Dieter

doi:10.1002/cite.201500092

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Development of the travelling wave bioreactor. Part I : design studies based on numerical models
Authors:	Kaiser, Stephan Kraume, Matthias Eibl, Dieter
DOI:	10.1002/cite.201500092
Published in:	Chemie Ingenieur Technik
Volume(Issue):	88
Issue:	1-2
Page(s):	77
Pages to:	85
Issue Date:	Feb-2016
Publisher / Ed. Institution:	Wiley
Publisher / Ed. Institution:	Weinheim
ISSN:	0009-286X 1522-2640
Language:	English
Subject (DDC):	660: Chemical engineering
Abstract:	In the travelling wave bioreactor (TWB) an orbital movement is used to set up a quasi-periodic wave motion in the partially filled, toroidal shaped vessel. Based on computational fluid dynamics (CFD) models, this study presents detailed analyses of the fluid flow in the TWB for a wide range of operational conditions. Even though the wave propagation is shown to be greatly influenced by the rotation, it was found that the regular vessel shape facilitates a predominantly tangential flow with low back mixing, irrespective of the operational conditions. Hence, the influence of different bioreactor geometries without and with baffles is examined. The study indicates that CFD models can be used as a valuable tool for bioreactor development, because it provides a deep insight into the bioreactor's hydrodynamics and can help to reduce the number of prototypes.
URI:	https://digitalcollection.zhaw.ch/handle/11475/2226
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Appears in collections:	Publikationen Life Sciences und Facility Management

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Kaiser, S., Kraume, M., & Eibl, D. (2016). Development of the travelling wave bioreactor. Part I : design studies based on numerical models. Chemie Ingenieur Technik, 88(1-2), 77–85. https://doi.org/10.1002/cite.201500092

Kaiser, S., Kraume, M. and Eibl, D. (2016) ‘Development of the travelling wave bioreactor. Part I : design studies based on numerical models’, Chemie Ingenieur Technik, 88(1-2), pp. 77–85. Available at: https://doi.org/10.1002/cite.201500092.

S. Kaiser, M. Kraume, and D. Eibl, “Development of the travelling wave bioreactor. Part I : design studies based on numerical models,” Chemie Ingenieur Technik, vol. 88, no. 1-2, pp. 77–85, Feb. 2016, doi: 10.1002/cite.201500092.

KAISER, Stephan, Matthias KRAUME und Dieter EIBL, 2016. Development of the travelling wave bioreactor. Part I : design studies based on numerical models. Chemie Ingenieur Technik. Februar 2016. Bd. 88, Nr. 1-2, S. 77–85. DOI 10.1002/cite.201500092

Kaiser, Stephan, Matthias Kraume, and Dieter Eibl. 2016. “Development of the Travelling Wave Bioreactor. Part I : Design Studies Based on Numerical Models.” Chemie Ingenieur Technik 88 (1-2): 77–85. https://doi.org/10.1002/cite.201500092.

Kaiser, Stephan, et al. “Development of the Travelling Wave Bioreactor. Part I : Design Studies Based on Numerical Models.” Chemie Ingenieur Technik, vol. 88, no. 1-2, Feb. 2016, pp. 77–85, https://doi.org/10.1002/cite.201500092.