Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-22211
Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: Portfolio frontier analysis : applying mean-variance analysis to health technology assessment for health systems under pressure
Authors: Baines, Darrin
Disegna, Marta
Hartwell, Christopher
et. al: No
DOI: 10.1016/j.socscimed.2021.113830
10.21256/zhaw-22211
Published in: Social Science & Medicine
Volume(Issue): 276
Issue: 113830
Issue Date: May-2021
Publisher / Ed. Institution: Elsevier
ISSN: 1873-5347
0277-9536
Language: English
Subjects: Decision-making; HTA; Health economics; Mean variance; Portfolio
Subject (DDC): 362: Health and social services
Abstract: The COVID-19 pandemic is challenging how healthcare technologies are evaluated, as new, more dynamic methods are required to test the cost effectiveness of alternative interventions during use rather than before initial adoption. Currently, health technology assessment (HTA) tends to be static and a priori: alternatives are compared before launch, and little evaluation occurs after implementation. We suggest a method that builds upon the current pre-launch HTA procedures by conceptualizing a mean-variance approach to the continuous evaluation of attainable portfolios of interventions in health systems. Our framework uses frontier analysis to identify the desirability of available health interventions so decision makers can choose diverse portfolios based upon information about expected returns and risks. This approach facilitates the extension of existing methods and assessments beyond the traditional concern with pre-adoption data, a much-needed innovation given the challenges posed by COVID-19.
URI: https://digitalcollection.zhaw.ch/handle/11475/22211
Fulltext version: Published version
License (according to publishing contract): CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Departement: School of Management and Law
Organisational Unit: International Management Institute (IMI)
Appears in collections:Publikationen School of Management and Law

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Baines, D., Disegna, M., & Hartwell, C. (2021). Portfolio frontier analysis : applying mean-variance analysis to health technology assessment for health systems under pressure. Social Science & Medicine, 276(113830). https://doi.org/10.1016/j.socscimed.2021.113830
Baines, D., Disegna, M. and Hartwell, C. (2021) ‘Portfolio frontier analysis : applying mean-variance analysis to health technology assessment for health systems under pressure’, Social Science & Medicine, 276(113830). Available at: https://doi.org/10.1016/j.socscimed.2021.113830.
D. Baines, M. Disegna, and C. Hartwell, “Portfolio frontier analysis : applying mean-variance analysis to health technology assessment for health systems under pressure,” Social Science & Medicine, vol. 276, no. 113830, May 2021, doi: 10.1016/j.socscimed.2021.113830.
BAINES, Darrin, Marta DISEGNA und Christopher HARTWELL, 2021. Portfolio frontier analysis : applying mean-variance analysis to health technology assessment for health systems under pressure. Social Science & Medicine. Mai 2021. Bd. 276, Nr. 113830. DOI 10.1016/j.socscimed.2021.113830
Baines, Darrin, Marta Disegna, and Christopher Hartwell. 2021. “Portfolio Frontier Analysis : Applying Mean-Variance Analysis to Health Technology Assessment for Health Systems under Pressure.” Social Science & Medicine 276 (113830). https://doi.org/10.1016/j.socscimed.2021.113830.
Baines, Darrin, et al. “Portfolio Frontier Analysis : Applying Mean-Variance Analysis to Health Technology Assessment for Health Systems under Pressure.” Social Science & Medicine, vol. 276, no. 113830, May 2021, https://doi.org/10.1016/j.socscimed.2021.113830.


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