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dc.contributor.authorKhojasteh, Abbas-
dc.contributor.authorSanchez-Munoz, Raul-
dc.contributor.authorMoyano, Elisabeth-
dc.contributor.authorBonfill, Mercedes-
dc.contributor.authorCusido, Rosa M.-
dc.contributor.authorEibl, Regine-
dc.contributor.authorPalazon, Javier-
dc.date.accessioned2021-03-14T16:55:44Z-
dc.date.available2021-03-14T16:55:44Z-
dc.date.issued2019-
dc.identifier.issn0981-9428de_CH
dc.identifier.issn1873-2690de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/22008-
dc.description.abstractRuscus aculeatus is a threatened medicinal plant whose main bioactive components, the ruscogenins, have long been used in the treatment of hemorrhoids and varicose veins, but recently demonstrated activity against some types of cancer. Plant cell biofactories could constitute an alternative to the whole plant as a source of ruscogenins. In this pipeline, despite the in vitro recalcitrance of R. aculeatus, after many attempts we developed friable calli and derived plant cell suspensions, and their ruscogenin production was compared with that of organized in vitro plantlet and root-rhizome cultures. Root-rhizomes showed a higher capacity for biomass and ruscogenin production than the cell suspensions and the yields were greatly improved by elicitation with coronatine. Although ruscogenins accumulate in plants mainly in the root-rhizome, it was demonstrated that the aerial part could play an important role in their biosynthesis, as production was higher in the whole plant than in the root-rhizome cultures.de_CH
dc.language.isoende_CH
dc.publisherElsevierde_CH
dc.relation.ispartofPlant Physiology and Biochemistryde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectPlant cell culturede_CH
dc.subjectRoot-rhizome culturede_CH
dc.subjectRuscus aculeatusde_CH
dc.subjectRuscogenin biosynthesisde_CH
dc.subject.ddc660.6: Biotechnologiede_CH
dc.titleBiotechnological production of ruscogenins in plant cell and organ cultures of Rescus aculeatusde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.1016/j.plaphy.2019.05.029de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end141de_CH
zhaw.pages.start133de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume141de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Khojasteh, A., Sanchez-Munoz, R., Moyano, E., Bonfill, M., Cusido, R. M., Eibl, R., & Palazon, J. (2019). Biotechnological production of ruscogenins in plant cell and organ cultures of Rescus aculeatus. Plant Physiology and Biochemistry, 141, 133–141. https://doi.org/10.1016/j.plaphy.2019.05.029
Khojasteh, A. et al. (2019) ‘Biotechnological production of ruscogenins in plant cell and organ cultures of Rescus aculeatus’, Plant Physiology and Biochemistry, 141, pp. 133–141. Available at: https://doi.org/10.1016/j.plaphy.2019.05.029.
A. Khojasteh et al., “Biotechnological production of ruscogenins in plant cell and organ cultures of Rescus aculeatus,” Plant Physiology and Biochemistry, vol. 141, pp. 133–141, 2019, doi: 10.1016/j.plaphy.2019.05.029.
KHOJASTEH, Abbas, Raul SANCHEZ-MUNOZ, Elisabeth MOYANO, Mercedes BONFILL, Rosa M. CUSIDO, Regine EIBL und Javier PALAZON, 2019. Biotechnological production of ruscogenins in plant cell and organ cultures of Rescus aculeatus. Plant Physiology and Biochemistry. 2019. Bd. 141, S. 133–141. DOI 10.1016/j.plaphy.2019.05.029
Khojasteh, Abbas, Raul Sanchez-Munoz, Elisabeth Moyano, Mercedes Bonfill, Rosa M. Cusido, Regine Eibl, and Javier Palazon. 2019. “Biotechnological Production of Ruscogenins in Plant Cell and Organ Cultures of Rescus Aculeatus.” Plant Physiology and Biochemistry 141: 133–41. https://doi.org/10.1016/j.plaphy.2019.05.029.
Khojasteh, Abbas, et al. “Biotechnological Production of Ruscogenins in Plant Cell and Organ Cultures of Rescus Aculeatus.” Plant Physiology and Biochemistry, vol. 141, 2019, pp. 133–41, https://doi.org/10.1016/j.plaphy.2019.05.029.


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