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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-21944
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dc.contributor.authorSchirmer, Cedric-
dc.contributor.authorMaschke, Rüdiger-
dc.contributor.authorPörtner, Ralf-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2021-03-05T13:33:06Z-
dc.date.available2021-03-05T13:33:06Z-
dc.date.issued2021-03-02-
dc.identifier.issn0175-7598de_CH
dc.identifier.issn1432-0614de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/21944-
dc.description.abstractNo matter the scale, stirred tank bioreactors are the most commonly used systems in biotechnological production processes. Single-use and reusable systems are supplied by several manufacturers. The type, size, and number of impellers used in these systems have a significant influence on the characteristics and designs of bioreactors. Depending on the desired application, classic shaft-driven systems, bearing-mounted drives, or stirring elements that levitate freely in the vessel may be employed. In systems with drive shafts, process hygiene requirements also affect the type of seal used. For sensitive processes with high hygienic requirements, magnetic-driven stirring systems, which have been the focus of much research in recent years, are recommended. This review provides the reader with an overview of the most common agitation and seal types implemented in stirred bioreactor systems, highlights their advantages and disadvantages, and explains their possible fields of application. Special attention is paid to the development of magnetically driven agitators, which are widely used in reusable systems and are also becoming more and more important in their single-use counterparts.de_CH
dc.language.isoende_CH
dc.publisherSpringerde_CH
dc.relation.ispartofApplied Microbiology and Biotechnologyde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectBioreactor agitationde_CH
dc.subjectMagnetic couplingde_CH
dc.subjectMechanical sealingde_CH
dc.subjectLip sealde_CH
dc.subjectHygienic requirementsde_CH
dc.subjectApplication trendsde_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleAn overview of drive systems and sealing types in stirred bioreactors used in biotechnological processesde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.1007/s00253-021-11180-7de_CH
dc.identifier.doi10.21256/zhaw-21944-
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Schirmer, C., Maschke, R., Pörtner, R., & Eibl, D. (2021). An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes. Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-021-11180-7
Schirmer, C. et al. (2021) ‘An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes’, Applied Microbiology and Biotechnology [Preprint]. Available at: https://doi.org/10.1007/s00253-021-11180-7.
C. Schirmer, R. Maschke, R. Pörtner, and D. Eibl, “An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes,” Applied Microbiology and Biotechnology, Mar. 2021, doi: 10.1007/s00253-021-11180-7.
SCHIRMER, Cedric, Rüdiger MASCHKE, Ralf PÖRTNER und Dieter EIBL, 2021. An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes. Applied Microbiology and Biotechnology. 2 März 2021. DOI 10.1007/s00253-021-11180-7
Schirmer, Cedric, Rüdiger Maschke, Ralf Pörtner, and Dieter Eibl. 2021. “An Overview of Drive Systems and Sealing Types in Stirred Bioreactors Used in Biotechnological Processes.” Applied Microbiology and Biotechnology, March. https://doi.org/10.1007/s00253-021-11180-7.
Schirmer, Cedric, et al. “An Overview of Drive Systems and Sealing Types in Stirred Bioreactors Used in Biotechnological Processes.” Applied Microbiology and Biotechnology, Mar. 2021, https://doi.org/10.1007/s00253-021-11180-7.


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