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Publikationstyp: Beitrag in wissenschaftlicher Zeitschrift
Art der Begutachtung: Peer review (Publikation)
Titel: In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment
Autor/-in: Dabrowska, Agnieszka K.
Adlhart, Christian
Spano, Fabrizio
Rotaru, Gelu-Marius
Derler, Siegfried
Zhai, Lina
Spencer, Nicolas D.
Rossi, René M.
DOI: 10.1116/1.4962547
10.21256/zhaw-1573
Erschienen in: Biointerphases
Band(Heft): 11
Heft: 3
Erscheinungsdatum: Aug-2016
Verlag / Hrsg. Institution: American Institute of Physics
Verlag / Hrsg. Institution: Maryland
ISSN: 1934-8630
1559-4106
Sprache: Englisch
Schlagwörter: Skin; Raman spectra; Spectral properties; Three dimensional microscopy; Proteins
Fachgebiet (DDC): 610: Medizin und Gesundheit
Zusammenfassung: Skin properties, structure and performance can be influenced by many internal and external factors, such as age, gender, lifestyle, skin diseases and a hydration level that can vary in relation to the environment. The aim of this work was to demonstrate the multifaceted influence of water on human skin through a combination of in vivo confocal Raman spectroscopy and images of volar-forearm skin captured with laser scanning confocal microscopy. By means of this pilot study, we have both qualitatively and quantitatively studied the influence of changing the depth-dependent hydration level of the stratum corneum (SC) on the real contact area (RCA), surface roughness and the dimensions of the primary lines and presented a new method for characterising the contact area for different states of the skin. The hydration level of the skin and the thickness of the SC increased significantly due to uptake of moisture derived from liquid water or, to a much lesser extent, from humidity present in the environment. Hydrated skin was smoother and exhibited higher RCA values. The highest rates of water uptake were observed for the upper few μm of skin and for short exposure times.
URI: https://digitalcollection.zhaw.ch/handle/11475/2185
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): CC BY 4.0: Namensnennung 4.0 International
Departement: Life Sciences und Facility Management
Organisationseinheit: Institut für Chemie und Biotechnologie (ICBT)
Enthalten in den Sammlungen:Publikationen Life Sciences und Facility Management

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Dabrowska, A. K., Adlhart, C., Spano, F., Rotaru, G.-M., Derler, S., Zhai, L., Spencer, N. D., & Rossi, R. M. (2016). In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment. Biointerphases, 11(3). https://doi.org/10.1116/1.4962547
Dabrowska, A.K. et al. (2016) ‘In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment’, Biointerphases, 11(3). Available at: https://doi.org/10.1116/1.4962547.
A. K. Dabrowska et al., “In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment,” Biointerphases, vol. 11, no. 3, Aug. 2016, doi: 10.1116/1.4962547.
DABROWSKA, Agnieszka K., Christian ADLHART, Fabrizio SPANO, Gelu-Marius ROTARU, Siegfried DERLER, Lina ZHAI, Nicolas D. SPENCER und René M. ROSSI, 2016. In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment. Biointerphases. August 2016. Bd. 11, Nr. 3. DOI 10.1116/1.4962547
Dabrowska, Agnieszka K., Christian Adlhart, Fabrizio Spano, Gelu-Marius Rotaru, Siegfried Derler, Lina Zhai, Nicolas D. Spencer, and René M. Rossi. 2016. “In Vivo Confirmation of Hydration-Induced Changes in Human-Skin Thickness, Roughness and Interaction with the Environment.” Biointerphases 11 (3). https://doi.org/10.1116/1.4962547.
Dabrowska, Agnieszka K., et al. “In Vivo Confirmation of Hydration-Induced Changes in Human-Skin Thickness, Roughness and Interaction with the Environment.” Biointerphases, vol. 11, no. 3, Aug. 2016, https://doi.org/10.1116/1.4962547.


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