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dc.contributor.otherSchneider, Peter-
dc.contributor.otherRiedl, Rainer-
dc.contributor.otherTigges, Marcel-
dc.contributor.otherGitzinger, Marc-
dc.contributor.otherPieren, Michel-
dc.contributor.otherLevi, Assaf-
dc.contributor.otherSephton, Mark-
dc.contributor.otherSchellhorn, Birgit-
dc.contributor.otherZüger, Patrik-
dc.contributor.otherBrand, Michael-
dc.contributor.otherGygax, Daniel-
dc.contributor.otherSpies, Peter-
dc.description.abstractThe invention relates to compounds and pharmaceutical compositions useful in combination with tetracyclines in the treatment of bacterial infections caused by Gram- positive and Gram-negative pathogens, with particular efficacy in tetracycline resistant strains. These compounds specifically bind to TetR and therefore prevent the transcriptional activation of tet resistance genes. The compounds have a potentiating effect on the activity of members of the tetracycline family, in particular of tetracycline, minocycline, doxycycline and tigecycline, in the treatment of tetracycline susceptible, intermediate and tetracycline resistant pathogens.de_CH
dc.description.sponsorshipBioVersys AGde_CH
dc.titleComposition for treatment of pathogens that are resistant to tetracyclinesde_CH
dc.title.alternativeZusammensetzung zur Behandlung von tetracyclinresistenten Pathogenende_CH
dc.title.alternativeComposition pour le traitement de pathogènes qui sont résistants aux tétracyclinesde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.webfeedCC Drug Discoveryde_CH
Appears in collections:Patente Life Sciences und Facility Management

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Schneider, P., Riedl, R., Tigges, M., Gitzinger, M., Pieren, M., Levi, A., Sephton, M., Schellhorn, B., Züger, P., Brand, M., Gygax, D., & Spies, P. (2015). Composition for treatment of pathogens that are resistant to tetracyclines (Patent No. EP2950793A1). https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1
Schneider, P. et al. (2015) ‘Composition for treatment of pathogens that are resistant to tetracyclines’. Available at: https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1.
P. Schneider et al., “Composition for treatment of pathogens that are resistant to tetracyclines,” EP2950793A1, Dec. 09, 2015 [Online]. Available: https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1
SCHNEIDER, Peter, Rainer RIEDL, Marcel TIGGES, Marc GITZINGER, Michel PIEREN, Assaf LEVI, Mark SEPHTON, Birgit SCHELLHORN, Patrik ZÜGER, Michael BRAND, Daniel GYGAX und Peter SPIES, 2015. Composition for treatment of pathogens that are resistant to tetracyclines [online]. EP2950793A1. 9 Dezember 2015. Verfügbar unter: https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1
Schneider, Peter, Rainer Riedl, Marcel Tigges, Marc Gitzinger, Michel Pieren, Assaf Levi, Mark Sephton, et al. 2015. Composition for treatment of pathogens that are resistant to tetracyclines. EP2950793A1, filed February 3, 2014, and issued December 9, 2015. https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1.
Schneider, Peter, et al. Composition for Treatment of Pathogens That Are Resistant to Tetracyclines. EP2950793A1, 9 Dec. 2015, https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1.

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