| Publication type: | Patent |
| Title: | Composition for treatment of pathogens that are resistant to tetracyclines |
| Inventor: | Schneider, Peter Riedl, Rainer Tigges, Marcel Gitzinger, Marc Pieren, Michel Levi, Assaf Sephton, Mark Schellhorn, Birgit Züger, Patrik Brand, Michael Gygax, Daniel Spies, Peter |
| Patent submitter: | BioVersys AG |
| Registration date: | 3-Feb-2014 |
| Issue Date: | 9-Dec-2015 |
| Publication number: | EP2950793 |
| metadata.zhaw.publication.code: | A1 |
| Published as: | EP2762134A1; EP2950793B1; US2015359791A1; US9682079B2; WO2014118361A1 |
| Language: | English |
| Abstract: | The invention relates to compounds and pharmaceutical compositions useful in combination with tetracyclines in the treatment of bacterial infections caused by Gram- positive and Gram-negative pathogens, with particular efficacy in tetracycline resistant strains. These compounds specifically bind to TetR and therefore prevent the transcriptional activation of tet resistance genes. The compounds have a potentiating effect on the activity of members of the tetracycline family, in particular of tetracycline, minocycline, doxycycline and tigecycline, in the treatment of tetracycline susceptible, intermediate and tetracycline resistant pathogens. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/21726 https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1 |
| Departement: | Life Sciences and Facility Management |
| Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
| Appears in collections: | Patente Life Sciences und Facility Management |
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