|Title:||Composition for treatment of pathogens that are resistant to tetracyclines|
|Patent submitter:||BioVersys AG|
|Published as:||EP2762134A1; EP2950793B1; US2015359791A1; US9682079B2; WO2014118361A1|
|Abstract:||The invention relates to compounds and pharmaceutical compositions useful in combination with tetracyclines in the treatment of bacterial infections caused by Gram- positive and Gram-negative pathogens, with particular efficacy in tetracycline resistant strains. These compounds specifically bind to TetR and therefore prevent the transcriptional activation of tet resistance genes. The compounds have a potentiating effect on the activity of members of the tetracycline family, in particular of tetracycline, minocycline, doxycycline and tigecycline, in the treatment of tetracycline susceptible, intermediate and tetracycline resistant pathogens.|
|Departement:||Life Sciences and Facility Management|
|Organisational Unit:||Institute of Chemistry and Biotechnology (ICBT)|
|Appears in collections:||Patente Life Sciences und Facility Management|
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Schneider, P., Riedl, R., Tigges, M., Gitzinger, M., Pieren, M., Levi, A., Sephton, M., Schellhorn, B., Züger, P., Brand, M., Gygax, D., & Spies, P. (2015). Composition for treatment of pathogens that are resistant to tetracyclines (Patent No. EP2950793A1). https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1
Schneider, P. et al. (2015) ‘Composition for treatment of pathogens that are resistant to tetracyclines’. Available at: https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1.
P. Schneider et al., “Composition for treatment of pathogens that are resistant to tetracyclines,” EP2950793A1, Dec. 09, 2015 [Online]. Available: https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1
Schneider, Peter, et al. Composition for Treatment of Pathogens That Are Resistant to Tetracyclines. EP2950793A1, 9 Dec. 2015, https://worldwide.espacenet.com/patent/search?q=pn%3DEP2950793A1.
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