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dc.contributor.authorGabel, Charles Philip-
dc.contributor.authorMokhtarinia, Hamid Reza-
dc.contributor.authorMelloh, Markus-
dc.date.accessioned2020-12-18T10:03:36Z-
dc.date.available2020-12-18T10:03:36Z-
dc.date.issued2020-10-19-
dc.identifier.issn0362-2436de_CH
dc.identifier.issn1528-1159de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/21096-
dc.description.abstractStudy Design Retrospective review of the literature. Objective To update recent trends in the use of magnetic resonance spectroscopy (MRS) analysis for chronic low back pain (CLBP). Summary of Background Data The lumbar multifidus muscle (MF) has drawn sustained interest for some time, particularly related to its structure, role in spinal stability, and its association and clinical significance with CLBP. Additionally, the presence of MF arthrogenic muscle inhibition (AMI) and its relation to induced CLBP, through depleted lumbar stabilization, has gained increased recognition. In contrast, the differential diagnostic use of MRS analysis has suggested specific links between the presence of MF myocellular lipid (MCL) infiltration and CLBP patients. Methods Review of the literature related to CLBP with the keywords MCL, MRS analysis and MF-AMI. Results No articles discussed CLBP using the three key concepts in a single context. The use of MRS analysis has the capacity to distinguish between extra-MCL (EMCL) and intra-MCL (IMCL) infiltration within the lumbar MF. It is suggested that EMCLs are more likely to be associated with age related change, while the IMCLs appear more likely to be associated with the presence of CLBP. The increased recognition of MF-AMI as a primary cause of CLBP, and the potential that AMI parallels the presence of IMCLs, facilitates possible use of MRS as a means to quantify the basis of lumbar MF-AMI CLBP, and that proportional IMCL changes in the MF could serve as a ‘proxy’ to indicate the effectiveness of interventions directed at MF activation. Conclusions It may be possible for IMCLs to serve as a ‘proxy’ prognostic marker of lumbar MF-AMI in CLBP patients. Further, if this assertion were correct, then reductions in IMCLs could potentially quantify recovery and the efficacy of rehabilitation management strategies directed at lumbar MF activation.de_CH
dc.language.isoende_CH
dc.publisherLippincott Williams & Wilkinsde_CH
dc.relation.ispartofSpinede_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectArthrogenic Muscle Inhibition (AMI)de_CH
dc.subjectIntra-Myo-Cellular Lipid (IMCL)de_CH
dc.subjectMultifidusde_CH
dc.subjectChronic Low Back Pain (CLBP)de_CH
dc.subject.ddc617.5: Orthopädische Chirurgiede_CH
dc.titleThe politics of chronic LBP: can we rely on a proxy-vote? : linking multifidus intra-myo-cellular lipid (IMCL) fatty infiltration with arthrogenic muscle inhibition induced chronic non-specific low back painde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Public Health (IPH)de_CH
dc.identifier.doi10.1097/BRS.0000000000003758de_CH
dc.identifier.pmid33079906de_CH
zhaw.funding.euNode_CH
zhaw.issue2de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end130de_CH
zhaw.pages.start129de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume46de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Gabel, C. P., Mokhtarinia, H. R., & Melloh, M. (2020). The politics of chronic LBP: can we rely on a proxy-vote? : linking multifidus intra-myo-cellular lipid (IMCL) fatty infiltration with arthrogenic muscle inhibition induced chronic non-specific low back pain. Spine, 46(2), 129–130. https://doi.org/10.1097/BRS.0000000000003758
Gabel, C.P., Mokhtarinia, H.R. and Melloh, M. (2020) ‘The politics of chronic LBP: can we rely on a proxy-vote? : linking multifidus intra-myo-cellular lipid (IMCL) fatty infiltration with arthrogenic muscle inhibition induced chronic non-specific low back pain’, Spine, 46(2), pp. 129–130. Available at: https://doi.org/10.1097/BRS.0000000000003758.
C. P. Gabel, H. R. Mokhtarinia, and M. Melloh, “The politics of chronic LBP: can we rely on a proxy-vote? : linking multifidus intra-myo-cellular lipid (IMCL) fatty infiltration with arthrogenic muscle inhibition induced chronic non-specific low back pain,” Spine, vol. 46, no. 2, pp. 129–130, Oct. 2020, doi: 10.1097/BRS.0000000000003758.
GABEL, Charles Philip, Hamid Reza MOKHTARINIA und Markus MELLOH, 2020. The politics of chronic LBP: can we rely on a proxy-vote? : linking multifidus intra-myo-cellular lipid (IMCL) fatty infiltration with arthrogenic muscle inhibition induced chronic non-specific low back pain. Spine. 19 Oktober 2020. Bd. 46, Nr. 2, S. 129–130. DOI 10.1097/BRS.0000000000003758
Gabel, Charles Philip, Hamid Reza Mokhtarinia, and Markus Melloh. 2020. “The Politics of Chronic LBP: Can We Rely on a Proxy-Vote? : Linking Multifidus Intra-Myo-Cellular Lipid (IMCL) Fatty Infiltration with Arthrogenic Muscle Inhibition Induced Chronic Non-Specific Low Back Pain.” Spine 46 (2): 129–30. https://doi.org/10.1097/BRS.0000000000003758.
Gabel, Charles Philip, et al. “The Politics of Chronic LBP: Can We Rely on a Proxy-Vote? : Linking Multifidus Intra-Myo-Cellular Lipid (IMCL) Fatty Infiltration with Arthrogenic Muscle Inhibition Induced Chronic Non-Specific Low Back Pain.” Spine, vol. 46, no. 2, Oct. 2020, pp. 129–30, https://doi.org/10.1097/BRS.0000000000003758.


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