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dc.contributor.authorSeidel, Stefan-
dc.contributor.authorWerner, Sören-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2020-12-11T13:39:05Z-
dc.date.available2020-12-11T13:39:05Z-
dc.date.issued2020-06-10-
dc.identifier.urihttps://www.levitronix.com/files/dl__documents/Levitronix%20Conferences/LBC%202020%20Webinar/EventAgendaJune10.pdfde_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/21013-
dc.description.abstractComputational Fluid Dynamics (CFD) is used in biotechnology to gain a deeper understanding of the underlying fluid flow in a great variety of process equipment, e.g. for fluid flow characterisation in bioreactors. This enables the reduction of resource-intensive prototyping, since CFD is used to determine optimal process conditions in silico. Typical process engineering investigations for bioreactors are mixing time, power input as well as shear and normal stress. Most of the biopharmaceutical production processes are accomplished with aerobe cells, and thus the process relies on sufficient gas mass transfer to supply enough oxygen to the culture broth, which has a considerable influence on cell growth and product yield. In recent years, CFD models have increasingly been coupled with population balance models (PBM) to calculate the gas bubble size distribution through breakup and coalescence. This coupling allows the simulation of oxygen distribution in polydisperse systems, like aerated bioreactors. This presentation shows recent developments in modelling bubble size distribution and gas mass transfer.de_CH
dc.language.isoende_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectBioreactorde_CH
dc.subjectCFD simulationde_CH
dc.subjectMultiphase modelingde_CH
dc.subjectOxygen transfer ratede_CH
dc.subjectPopulation balance modelingde_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleCFD for process engineering characterizationde_CH
dc.typeKonferenz: Sonstigesde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.conference.detailsLevitronix Bioprocessing Conference, Webinar Part 3, 10 June 2020de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.publication.reviewKeine Begutachtungde_CH
zhaw.webfeedVerfahrenstechnikde_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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