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Title: Hosting the plant cells in vitro : recent trends in bioreactors
Authors : Georgiev, Milen I.
Eibl-Schindler, Regine
Zhong, Jian-Jiang
Published in : Applied Microbiology and Biotechnology
Volume(Issue) : 97
Issue : 9
Pages : 3787
Pages to: 3800
Publisher / Ed. Institution : Springer
Publisher / Ed. Institution: Heidelberg, Berlin
Issue Date: 2013
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Publication)
Language : English
Subject (DDC) : 660: Chemical engineering
Abstract: Biotechnological production of high-value metabolites and therapeutic proteins by plant in vitro systems has been considered as an attractive alternative of classical technologies. Numerous proof-of-concept studies have illustrated the feasibility of scaling up plant in vitro system-based processes while keeping their biosynthetic potential. Moreover, several commercial processes have been established so far. Though the progress on the field is still limited, in the recent years several bioreactor configurations has been developed (e.g., so-called single-use bioreactors) and successfully adapted for growing plant cells in vitro. This review highlights recent progress and limitations in the bioreactors for plant cells and outlines future perspectives for wider industrialization of plant in vitro systems as “green cell factories” for sustainable production of value-added molecules.
Departement: Life Sciences und Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Publication type: Article in scientific Journal
DOI : 10.1007/s00253-013-4817-x
ISSN: 0175-7598
Restricted until : 2019-01-01
Appears in Collections:Publikationen Life Sciences und Facility Management

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