Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles

Bendixen, Nina; Losert, Sabrina; Adlhart, Christian; Lattuada, Marco; Ulrich, Andrea

doi:10.1016/j.chroma.2014.01.066

Full metadata record

DC Field	Value	Language
dc.contributor.author	Bendixen, Nina	-
dc.contributor.author	Losert, Sabrina	-
dc.contributor.author	Adlhart, Christian	-
dc.contributor.author	Lattuada, Marco	-
dc.contributor.author	Ulrich, Andrea	-
dc.date.accessioned	2018-01-17T10:31:36Z	-
dc.date.available	2018-01-17T10:31:36Z	-
dc.date.issued	2014	-
dc.identifier.issn	0021-9673	de_CH
dc.identifier.issn	1873-3778	de_CH
dc.identifier.uri	https://digitalcollection.zhaw.ch/handle/11475/2080	-
dc.description.abstract	Asymmetric flow field flow fractionation operated in a multidetector approach (A4F-MDA) is a powerful tool to perform size-classified nanoparticle analysis. Recently several publications mentioned insufficient recovery rates and even retention time shifts attributed to unspecific membrane–particle interactions. One hypothesis to explain this phenomenon is based on the surface charge (zeta-potential) of the membrane material and the particle. In this study, we investigated in how far the ζ-potential of A4F membrane and particles would determine the outcome of A4F in terms of feasibility, separation efficiency, retention time, and recovery rate, or whether other factors such as membrane morphology and particle size were equally important. We systematically studied the influence of the ζ-potential on the interactions between the most commonly used A4F membrane materials and two representative types of titanium dioxide nanoparticles (TiO2 NP). Furthermore the effect of different carrier media and additional surfactants on the surface charge of membranes and particles was investigated and the influence of the particle size and the particle concentration on the recovery rate was evaluated. We found that the eligibility of an A4F method can be predicted based on the ζ-potential of the NPs and the A4F membrane. Furthermore knowing the ζ-potential allows to tuning the separation efficiency of an A4F method. On the other hand we observed significant shifts in retention time for different membrane materials that impede the determination of particle size based on the classical A4F theory. These shifts cannot be attributed to the ζ-potential. Also the ζ-potential does not account for varying recovery rates of different particle types, instead the particle size seems to be the limiting factor. Therefore, the proper characterization of a polydisperse sample remains a challenge.	de_CH
dc.language.iso	en	de_CH
dc.publisher	Elsevier	de_CH
dc.relation.ispartof	Journal of Chromatography A	de_CH
dc.rights	Licence according to publishing contract	de_CH
dc.subject	Membrane	de_CH
dc.subject	Titanium dioxide nanoparticle	de_CH
dc.subject	Interaction	de_CH
dc.subject	Asymmetric flow field flow fractionation (A4F)	de_CH
dc.subject	Zeta-potential	de_CH
dc.subject.ddc	620: Ingenieurwesen	de_CH
dc.title	Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles	de_CH
dc.type	Beitrag in wissenschaftlicher Zeitschrift	de_CH
dcterms.type	Text	de_CH
zhaw.departement	Life Sciences und Facility Management	de_CH
zhaw.organisationalunit	Institut für Chemie und Biotechnologie (ICBT)	de_CH
zhaw.publisher.place	Amsterdam	de_CH
dc.identifier.doi	10.1016/j.chroma.2014.01.066	de_CH
zhaw.funding.eu	No	de_CH
zhaw.originated.zhaw	Yes	de_CH
zhaw.pages.end	100	de_CH
zhaw.pages.start	92	de_CH
zhaw.publication.status	publishedVersion	de_CH
zhaw.volume	1334	de_CH
zhaw.publication.review	Peer review (Publikation)	de_CH
Appears in collections:	Publikationen Life Sciences und Facility Management

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Bendixen, N., Losert, S., Adlhart, C., Lattuada, M., & Ulrich, A. (2014). Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles. Journal of Chromatography A, 1334, 92–100. https://doi.org/10.1016/j.chroma.2014.01.066

Bendixen, N. et al. (2014) ‘Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles’, Journal of Chromatography A, 1334, pp. 92–100. Available at: https://doi.org/10.1016/j.chroma.2014.01.066.

N. Bendixen, S. Losert, C. Adlhart, M. Lattuada, and A. Ulrich, “Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles,” Journal of Chromatography A, vol. 1334, pp. 92–100, 2014, doi: 10.1016/j.chroma.2014.01.066.

BENDIXEN, Nina, Sabrina LOSERT, Christian ADLHART, Marco LATTUADA und Andrea ULRICH, 2014. Membrane-particle interactions in an asymmetric flow field flow fractionation channel studied with titanium dioxide nanoparticles. Journal of Chromatography A. 2014. Bd. 1334, S. 92–100. DOI 10.1016/j.chroma.2014.01.066

Bendixen, Nina, Sabrina Losert, Christian Adlhart, Marco Lattuada, and Andrea Ulrich. 2014. “Membrane-Particle Interactions in an Asymmetric Flow Field Flow Fractionation Channel Studied with Titanium Dioxide Nanoparticles.” Journal of Chromatography A 1334: 92–100. https://doi.org/10.1016/j.chroma.2014.01.066.

Bendixen, Nina, et al. “Membrane-Particle Interactions in an Asymmetric Flow Field Flow Fractionation Channel Studied with Titanium Dioxide Nanoparticles.” Journal of Chromatography A, vol. 1334, 2014, pp. 92–100, https://doi.org/10.1016/j.chroma.2014.01.066.