Title: Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb.
Authors : Danova, Kalina
Wolfram, Evelyn
Pedrussio, Simona
Koleva, Petya
Aneva, Ida
Evstatieva, Luba
Proceedings: Planta Medica International Open
Volume(Issue) : 4
Conference details: 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, September 3 rd to 6th 2017
Publisher / Ed. Institution : Thieme
Issue Date: 2017
Language : Englisch / English
Subject (DDC) : 572: Biochemie
580: Pflanzen (Botanik)
660.6: Biotechnologie
Abstract: In vitro culture of Balkan endemic medicinal plant Sideritis scardica was previously initiated and different approaches for influencing the productivity of polyphenolics have been applied [1]. The present work discusses the spectrophotometric and HPTLC phenolics and flavonoids phytochemical profiling, DPPH radical scavenging activity and lipase and acetylcholinesterase inhibition assay of total methanol extract of plant material of the in vitro cultured plant. The following plant growth regulators were added to the control medium: 0.2 mg/L benzyl adenine (BA) + 0.02 mg/L 1-Naphthaleneacetic acid (NAA) (Sm); 0.2 mg/L BA + 0.5 mg/L NAA (Sr_1), 0.2 mg/L BA + 1.0 mg/L NAA (Sr_2), 0.5 mg/L BA + 0.5 mg/L NAA (Sr_3) and 0.5 mg/L BA + 1.0 mg/L NAA (Sr_4). As a general observation all treatments increased significantly the survival rate of explants, as well as polyphenolics productions as compared with the non-treated control. Strong relation between polyphenolic content and radical scavenging capacity were recorded and one probable lipase and and 2 – 4 components with acetylcholinesterase inhibition activity were identified. As a result of the work in vitro culture systems for optimal biomass production and secondary metabolites yield were selected. This work was financed by the PhytoBalk project (BSRP, grant No. IZEBZ0_142989). [1] Koleva P, Petrova N, Krumova S, Velikova V, Aneva I, Evstatieva L, Wolfram E, Danova K (2016) Planta Med 2016; 82(S 01): S1-S381
Departement: Life Sciences und Facility Management
Publication type: Konferenz: Poster / Conference Poster
Type of review: Peer review (Abstract)
DOI : 10.1055/s-0037-1608366
ISSN: 2509-6656
URI: https://digitalcollection.zhaw.ch/handle/11475/1966
License (according to publishing contract) : Lizenz gemäss Verlagsvertrag / Licence according to publishing contract
Appears in Collections:Publikationen Life Sciences und Facility Management

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