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dc.contributor.authorWolfram, Evelyn-
dc.contributor.authorMeier, Nadja-
dc.contributor.authorPeter, Samuel-
dc.contributor.authorMeier, Beat-
dc.date.accessioned2018-01-10T12:33:48Z-
dc.date.available2018-01-10T12:33:48Z-
dc.date.issued2017-
dc.identifier.issn2509-6656de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/1960-
dc.description.abstractRubi ideae folium, a traditional remedy for pain relief and smooth muscle relacation especially as support before and during child delivery has been recently assessed by the HMPC [1] and has not yet been monographed in the European Pharmacopeia. The development of the valid quality control methods for identification, contaminants and content assay is ongoing. This study developed an HPTLC method according to the novel. Four different mobile phases have been tested until the ideal mix of anhydrous formic acid R, water R, ethylacetate R (10:10:80, V/V/V) was chosen for good fingerprint separation. Hyperosid (2 mg/10 mL in methanol) und Chlorogenic acid (2 mg/10 mL in methanol) serve as System Suitability Solution for SST and Rutin (2 mg in 10 mL Methanol) applied as Rf reference value. The results are a clear and well separated fingerprint – the prominent yellow band has not yet clearly identified. Results from TLC-ESI-MS and TLC-MALDI analysis give mass values which suggest the presence of quercitin glucoronide. However these results need to be confirmed by further in depth isolation and structure elucidation invetigations. [1] EMA (2012), Assessment report on Rubus idaeus L, folium. Commitee on Herbal medicinal products. EMA/HMPC/44209/2012de_CH
dc.language.isoende_CH
dc.publisherThiemede_CH
dc.relation.ispartofPlanta Medica International Opende_CH
dc.rightsLicence according to publishing contractde_CH
dc.subject.ddc572: Biochemiede_CH
dc.subject.ddc615: Pharmakologie und Therapeutikde_CH
dc.subject.ddc660.6: Biotechnologiede_CH
dc.titleDevelopment of an HPTLC identification method in new Ph Eur monograph for Rubi ideae folium (raspberry leaves)de_CH
dc.typeKonferenz: Posterde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.1055/s-0037-1608528de_CH
zhaw.conference.details65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume4de_CH
zhaw.publication.reviewPeer review (Abstract)de_CH
zhaw.webfeedPhytopharmaziede_CH
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Wolfram, E., Meier, N., Peter, S., & Meier, B. (2017). Development of an HPTLC identification method in new Ph Eur monograph for Rubi ideae folium (raspberry leaves) [Conference poster]. Planta Medica International Open, 4. https://doi.org/10.1055/s-0037-1608528
Wolfram, E. et al. (2017) ‘Development of an HPTLC identification method in new Ph Eur monograph for Rubi ideae folium (raspberry leaves)’, in Planta Medica International Open. Thieme. Available at: https://doi.org/10.1055/s-0037-1608528.
E. Wolfram, N. Meier, S. Peter, and B. Meier, “Development of an HPTLC identification method in new Ph Eur monograph for Rubi ideae folium (raspberry leaves),” in Planta Medica International Open, 2017, vol. 4. doi: 10.1055/s-0037-1608528.
WOLFRAM, Evelyn, Nadja MEIER, Samuel PETER und Beat MEIER, 2017. Development of an HPTLC identification method in new Ph Eur monograph for Rubi ideae folium (raspberry leaves). In: Planta Medica International Open. Conference poster. Thieme. 2017
Wolfram, Evelyn, Nadja Meier, Samuel Peter, and Beat Meier. 2017. “Development of an HPTLC Identification Method in New Ph Eur Monograph for Rubi Ideae Folium (Raspberry Leaves).” Conference poster. In Planta Medica International Open. Vol. 4. Thieme. https://doi.org/10.1055/s-0037-1608528.
Wolfram, Evelyn, et al. “Development of an HPTLC Identification Method in New Ph Eur Monograph for Rubi Ideae Folium (Raspberry Leaves).” Planta Medica International Open, vol. 4, Thieme, 2017, https://doi.org/10.1055/s-0037-1608528.


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