Publication type: Contribution to magazine or newspaper
Title: Integration of chemical-optical oxygen and pH sensors in existing control units : cultivation monitoring in a glass bioreactor system with subsequently integrated sensor spots
Authors: Schirmer, Cedric
Ott, Vivian
John, Gernot T.
Eibl, Dieter
et. al: No
Published in: PreSens Publications
Issue Date: 2020
Publisher / Ed. Institution: PreSens Precision Sensing
Language: English
Subject (DDC): 660: Chemical engineering
Abstract: The use of chemical-optical sensors for monitoring a cultivation using bioreactors with an already existing control unit requires the input of additional measuring signals. For this purpose, the digital signal often must be converted into an analog signal. This can be done by acquiring the online measurement data of the pH and dissolved oxygen (DO) sensor spot signals with the software PreSens Measurement Studio 2 and then converting them via a Complementary Straight Binary (CSB) Converter and transmitting them to the control unit. The signals sent to the control unit can be further used to monitor and control pH and DO profiles. The exact and correct functioning of the experimental setup could be verified in experiments with Chinese Hamster Ovary (CHO) and Escherichia coli cells and should also be suitable for use in combination with other bioreactor systems and control units from different manufacturers.
Fulltext version: Published version
License (according to publishing contract): Not specified
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:Publikationen Life Sciences und Facility Management

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