Publication type: Book
Type of review: No review
Title: Recommendation for biological evaluation of bioreactor performance for microbial processes
Authors: Schirmer, Cedric
Dreher, Thomas
Leupold, Marco
Glaser, Robert
Castan, Andreas
Brown, Jason
Eibl, Dieter
Glöckler, Rainer
et. al: No
Extent: 35
Issue Date: Sep-2019
Edition: 2. revised edition
Publisher / Ed. Institution: DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e.V.
Publisher / Ed. Institution: Frankfurt am Main
ISBN: 978-3-89746-222-9
Language: English
Subject (DDC): 660: Chemical engineering
Abstract: The Escherichia coli model process described in the recommendation also makes it possible to characterise the biological performance of a system. The standardised process aims to determine the performance of bioreactors, in particular, single-use bioreactors, and to evaluate their suitability for microbial applications. Since microbial processes place high demands on the bioreactor system with regard to oxygen transfer, this is of particular importance; another important parameter is heat removal. The associated Excel tool offers the possibility of a standardised evaluation so that a comparison across bioreactor systems is possible. Calculations, e.g. of the volumetric mass transfer coefficient, will be performed automatically after input of the raw data. Recommendation and Excel tool were developed by the "Single-Use Microbial" working group of DECHEMA's expert group "Single-Use Technology in Biopharmaceutical Manufacturing".
Fulltext version: Published version
License (according to publishing contract): Not specified
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Appears in Collections:Publikationen Life Sciences und Facility Management

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