Title: The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis
Authors : Metsios, George S.
Moe, R. H.
van der Esch, M.
van Zanten, J. J. C. S. Veldhuijzen
Fenton, S. A. M.
Koutedakis, Y.
Vitalis, P.
Kennedy, N.
Brodin, N.
Bostrom, C.
Swinnen, T. W.
Tzika, K.
Niedermann Schneider, Karin
Nikiphorou, E.
Fragoulis, G. E.
Vlieland, T. P. V. M.
Van den Ende, C. H. M.
Kitas, George D.
et. al : No
Published in : Rheumatology International
Publisher / Ed. Institution : Springer
Issue Date: 4-Dec-2019
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (publication)
Language : English
Subjects : Autoimmune disease; Cardiovascular disease; Exercise; Inflammation; Non-communicable disease; Physical activity; Rehabilitation; Rheumatoid arthritis
Subject (DDC) : 616.7: Diseases of musculoskeletal system and orthopaedics
Abstract: Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.
Departement: Health Professions
Organisational Unit: Institute of Physiotherapy (IPT)
Publication type: Article in scientific journal
DOI : 10.1007/s00296-019-04483-6
ISSN: 0172-8172
1437-160X
URI: https://digitalcollection.zhaw.ch/handle/11475/18957
Appears in Collections:Publikationen Gesundheit

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