The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis

Metsios, George S.; Moe, R. H.; van der Esch, M.; van Zanten, J. J. C. S. Veldhuijzen; Fenton, S. A. M.; Koutedakis, Y.; Vitalis, P.; Kennedy, N.; Brodin, N.; Bostrom, C.; Swinnen, T. W.; Tzika, K.; Niedermann Schneider, Karin; Nikiphorou, E.; Fragoulis, G. E.; Vlieland, T. P. V. M.; Van den Ende, C. H. M.; Kitas, George D.

doi:10.1007/s00296-019-04483-6

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis
Authors:	Metsios, George S. Moe, R. H. van der Esch, M. van Zanten, J. J. C. S. Veldhuijzen Fenton, S. A. M. Koutedakis, Y. Vitalis, P. Kennedy, N. Brodin, N. Bostrom, C. Swinnen, T. W. Tzika, K. Niedermann Schneider, Karin Nikiphorou, E. Fragoulis, G. E. Vlieland, T. P. V. M. Van den Ende, C. H. M. Kitas, George D.
et. al:	No
DOI:	10.1007/s00296-019-04483-6
Published in:	Rheumatology International
Issue Date:	4-Dec-2019
Publisher / Ed. Institution:	Springer
ISSN:	0172-8172 1437-160X
Language:	English
Subjects:	Autoimmune disease; Cardiovascular disease; Exercise; Inflammation; Non-communicable disease; Physical activity; Rehabilitation; Rheumatoid arthritis
Subject (DDC):	616.7: Diseases of musculoskeletal system and orthopaedics
Abstract:	Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.
URI:	https://kclpure.kcl.ac.uk/portal/en/publications/the-effects-of-exercise-on-cardiovascular-disease-risk-factors-an https://digitalcollection.zhaw.ch/handle/11475/18957
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Health Sciences
Organisational Unit:	Institute of Physiotherapy (IPT)
Appears in collections:	Publikationen Gesundheit

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Metsios, G. S., Moe, R. H., van der Esch, M., van Zanten, J. J. C. S. V., Fenton, S. A. M., Koutedakis, Y., Vitalis, P., Kennedy, N., Brodin, N., Bostrom, C., Swinnen, T. W., Tzika, K., Niedermann Schneider, K., Nikiphorou, E., Fragoulis, G. E., Vlieland, T. P. V. M., Van den Ende, C. H. M., & Kitas, G. D. (2019). The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis. Rheumatology International. https://doi.org/10.1007/s00296-019-04483-6

Metsios, G.S. et al. (2019) ‘The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis’, Rheumatology International [Preprint]. Available at: https://doi.org/10.1007/s00296-019-04483-6.

G. S. Metsios et al., “The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis,” Rheumatology International, Dec. 2019, doi: 10.1007/s00296-019-04483-6.

METSIOS, George S., R. H. MOE, M. VAN DER ESCH, J. J. C. S. Veldhuijzen VAN ZANTEN, S. A. M. FENTON, Y. KOUTEDAKIS, P. VITALIS, N. KENNEDY, N. BRODIN, C. BOSTROM, T. W. SWINNEN, K. TZIKA, Karin NIEDERMANN SCHNEIDER, E. NIKIPHOROU, G. E. FRAGOULIS, T. P. V. M. VLIELAND, C. H. M. VAN DEN ENDE und George D. KITAS, 2019. The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis. Rheumatology International [online]. 4 Dezember 2019. DOI 10.1007/s00296-019-04483-6. Verfügbar unter: https://kclpure.kcl.ac.uk/portal/en/publications/the-effects-of-exercise-on-cardiovascular-disease-risk-factors-an

Metsios, George S., R. H. Moe, M. van der Esch, J. J. C. S. Veldhuijzen van Zanten, S. A. M. Fenton, Y. Koutedakis, P. Vitalis, et al. 2019. “The Effects of Exercise on Cardiovascular Disease Risk Factors and Cardiovascular Physiology in Rheumatoid Arthritis.” Rheumatology International, December. https://doi.org/10.1007/s00296-019-04483-6.

Metsios, George S., et al. “The Effects of Exercise on Cardiovascular Disease Risk Factors and Cardiovascular Physiology in Rheumatoid Arthritis.” Rheumatology International, Dec. 2019, https://doi.org/10.1007/s00296-019-04483-6.