Title: Verfahren und Vorrichtung für die Bestimmung von Substrat- und Produktkonzentrationen in einem Medium
Inventor : Wolfram, Evelyn
Franz, Andreas
Weuster-Botz, Dirk
Wandrey, Christian
Arnold, Matthias
Patent submitter: Forschungszentrum Jülich GmbH
Issue Date: 19-Sep-2000
Language : German
English
Subject (DDC) : 620: Engineering
Abstract: The invention relates to a method for the determination of analyte concentrations in liquid and/or gaseous media, whereby several probes withdraw at least one analyte from several sampling regions (3), across a semi-permeable membrane (2), by time-controlled diffusion of the at least one analyte between the relevant medium and a diffusion medium, which is fed to the sampling regions (3) through fluid lines (5a, 5b), by means of at least one pump (6). The diffusion medium is removed from the sampling region, with concomitant introduction of new diffusion medium and led to at least one detector (7) and analysed by the same. Said pump (6) works continuously and the diffusion medium may be alternately pumped to the fluid line sections (5b), by means of a multiple valve arrangement or a multiway-valve (12), arranged in series with the sampling regions (3). The invention is characterised in that the detector (7) can be continuously fed with diffusion medium by means of the fluid line sections (5b) and the bypass line (20).;A detector and a pump are additionally connected by a bypass line (20) which is connected to the valve arrangement (12). The diffusion medium is continuously introduced to the detector via the fluid line sections and the bypass line. Determining substrate and product concentrations in liquid and/or gaseous media comprises withdrawing at least one analyte from several sampling regions (3) across a semi-permeable membrane (2) by time-controlled diffusion of the analyte between the relevant medium and a diffusion medium which is fed to the sampling regions via fluid lines (5a, 5b) by means of a pump (6). The diffusion medium is removed from the sampling regions with the simultaneous introduction of a new diffusion medium and led to a detector (7) and analyzed to determine the analyte concentration. The pump works continuously and the diffusion medium is fed to the fluid line sections via a multiple valve arrangement (12) connected to the sample regions. The detector and the pump are additionally connected by a bypass line (20) which is connected to the valve arrangement (12). The diffusion medium is continuously introduced to the detector via the fluid line sections and the bypass line. An independent claim is also included for a device for carrying out the process.
Further description : Also published as: DE10024992(A1), EP1285249(A1), US2004029170(A1), WO0190718(A1)
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Publication type: Patent
Patentnumber : DE10024992
metadata.zhaw.publication.code: A1
URI: https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011206&DB=&locale=de_EP&CC=DE&NR=10024992A1&KC=A1
https://digitalcollection.zhaw.ch/handle/11475/17356
Appears in Collections:Patente Life Sciences und Facility Management

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