Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3277
Title: Different haemodynamic (24-h ambulatory blood-pressure monitoring) and rennin-inhibiting effect of a 1 week treatment with enalapril and lisinopril
Authors : Cocco, G.
Hari, Jürg J.
Published in : Clinical cardiology
Volume(Issue) : 14
Issue : 1
Pages : 881
Pages to: 884
Publisher / Ed. Institution : McGraw
Issue Date: 1991
License (according to publishing contract) : CC BY 4.0: Attribution 4.0 International
Type of review: Not specified
Language : English
Subjects : ACE inhibitor; Enalapril; Lisinopril; 24-h ambulatory blood pressure monitoring
Subject (DDC) : 615: Pharmacology and therapeutics
616: Internal medicine and diseases
Abstract: Ambulatory blood pressure and heart rate monitoring were used for comparing the antihypertensive effect of a 1 -week treatment with enalapril and lisinopril 10 mg once daily (double-blind crossover placebo-controlled d y ) . Welve outpatients with mild to moderate hypertension were treated. Both drugs had a significant and identical hypotensive effect. Neither drug affected the diurnal rhythm of blood pressure or heart rate. Therefore the two drugs are equipotent antihypertensive agents. Both drugs inhibited ACE activity to a highly significant extent, but in this regard lisinopril was more effective than enalapril. However, lisinopril's greater ACE inhibition was not accompanied by a greater hypotensive effect. The clinical value of this difference is not yet established.
Departement: School of Management and Law
Organisational Unit: Institute of Marketing Management (IMM)
Publication type: Article in scientific Journal
DOI : 10.1002/clc.4960141105
10.21256/zhaw-3277
ISSN: 0891-2092
URI: https://digitalcollection.zhaw.ch/handle/11475/17105
Appears in Collections:Publikationen School of Management and Law

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