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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3342
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dc.contributor.authorSchikowski, Tamara-
dc.contributor.authorSchaffner, Emmanuel-
dc.contributor.authorMeier, Flurina-
dc.contributor.authorPhuleria, Harish C.-
dc.contributor.authorVierkötter, Andrea-
dc.contributor.authorSchindler, Christian-
dc.contributor.authorKriemler, Susi-
dc.contributor.authorZemp, Elisabeth-
dc.contributor.authorKrämer, Ursula-
dc.contributor.authorBridevaux, Pierre-Olivier-
dc.contributor.authorRochat, Thierry-
dc.contributor.authorSchwart, Joel-
dc.contributor.authorKünzli, Nino-
dc.contributor.authorProbst-Hensch, Nicole-
dc.date.accessioned2019-03-29T08:19:59Z-
dc.date.available2019-03-29T08:19:59Z-
dc.date.issued2013-
dc.identifier.issn0091-6765de_CH
dc.identifier.issn1552-9924de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/16419-
dc.descriptionAll documents published by EHP are in the public domain. PDF copies of published articles can be freely shared and distributed without permission from either EHP or the authors.de_CH
dc.description.abstractBackground: Air pollution and obesity are hypothesized to contribute to accelerated decline in lung function with age through their inflammatory properties. Objective: We investigated whether the previously reported association between improved air quality and lung health in the population-based SAPALDIA cohort is modified by obesity. Methods: We used adjusted mixed-model analyses to estimate the association of average body mass index (BMI) and changes in particulate matter with aerodynamic diameter = 10 µm (PM10; ΔPM10) with lung function decline over a 10-year follow-up period. Results: Lung function data and complete information were available for 4,664 participants. Age-related declines in lung function among participants with high average BMI were more rapid for FVC (forced vital capacity), but slower for FEV1/FVC (forced expiratory volume in 1 sec/FVC) and FEF25-75 (forced expiratory flow at 25-75%) than declines among those with low or normal average BMI. Improved air quality was associated with attenuated reductions in FEV1/FVC, FEF25-75, and FEF25-75/FVC over time among low- and normal-BMI participants, but not overweight or obese participants. The attenuation was most pronounced for ΔFEF25-75/FVC (30% and 22% attenuation in association with a 10-µg/m3 decrease in PM10 among low- and normal-weight participants, respectively.) Conclusion: Our results point to the importance of considering health effects of air pollution exposure and obesity in parallel. Further research must address the mechanisms underlying the observed interaction.de_CH
dc.language.isoende_CH
dc.publisherNational Institute of Environmental Health Sciencesde_CH
dc.relation.ispartofEnvironmental Health Perspectivesde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleImproved air quality and attenuated lung function decline : modification by obesity in the SAPALDIA cohortde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Management and Lawde_CH
zhaw.organisationalunitWinterthurer Institut für Gesundheitsökonomie (WIG)de_CH
dc.identifier.doi10.21256/zhaw-3342-
dc.identifier.doi10.1289/ehp.1206145de_CH
zhaw.funding.euNode_CH
zhaw.issue9de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end1039de_CH
zhaw.pages.start1034de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume121de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
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Schikowski, T., Schaffner, E., Meier, F., Phuleria, H. C., Vierkötter, A., Schindler, C., Kriemler, S., Zemp, E., Krämer, U., Bridevaux, P.-O., Rochat, T., Schwart, J., Künzli, N., & Probst-Hensch, N. (2013). Improved air quality and attenuated lung function decline : modification by obesity in the SAPALDIA cohort. Environmental Health Perspectives, 121(9), 1034–1039. https://doi.org/10.21256/zhaw-3342
Schikowski, T. et al. (2013) ‘Improved air quality and attenuated lung function decline : modification by obesity in the SAPALDIA cohort’, Environmental Health Perspectives, 121(9), pp. 1034–1039. Available at: https://doi.org/10.21256/zhaw-3342.
T. Schikowski et al., “Improved air quality and attenuated lung function decline : modification by obesity in the SAPALDIA cohort,” Environmental Health Perspectives, vol. 121, no. 9, pp. 1034–1039, 2013, doi: 10.21256/zhaw-3342.
SCHIKOWSKI, Tamara, Emmanuel SCHAFFNER, Flurina MEIER, Harish C. PHULERIA, Andrea VIERKÖTTER, Christian SCHINDLER, Susi KRIEMLER, Elisabeth ZEMP, Ursula KRÄMER, Pierre-Olivier BRIDEVAUX, Thierry ROCHAT, Joel SCHWART, Nino KÜNZLI und Nicole PROBST-HENSCH, 2013. Improved air quality and attenuated lung function decline : modification by obesity in the SAPALDIA cohort. Environmental Health Perspectives. 2013. Bd. 121, Nr. 9, S. 1034–1039. DOI 10.21256/zhaw-3342
Schikowski, Tamara, Emmanuel Schaffner, Flurina Meier, Harish C. Phuleria, Andrea Vierkötter, Christian Schindler, Susi Kriemler, et al. 2013. “Improved Air Quality and Attenuated Lung Function Decline : Modification by Obesity in the SAPALDIA Cohort.” Environmental Health Perspectives 121 (9): 1034–39. https://doi.org/10.21256/zhaw-3342.
Schikowski, Tamara, et al. “Improved Air Quality and Attenuated Lung Function Decline : Modification by Obesity in the SAPALDIA Cohort.” Environmental Health Perspectives, vol. 121, no. 9, 2013, pp. 1034–39, https://doi.org/10.21256/zhaw-3342.


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