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Title: Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells
Authors : Jonsdottir, Hulda R.
Delaval, Mathilde
Leni, Zaira
Keller, Alejandro
Brem, Benjamin T.
Siegerist, Frithjof
Schönenberger, David
Durdina, Lukas
Elser, Miriam
Burtscher, Heinz
Liati, Anthi
Geiser, Marianne
Published in : Communications Biology
Volume(Issue) : 2
Issue : 90
Publisher / Ed. Institution : Springer
Issue Date: 2019
License (according to publishing contract) : CC BY 4.0: Attribution 4.0 International
Type of review: Peer review (publication)
Language : English
Subjects : Mechanisms of disease; Respiratory tract diseases
Subject (DDC) : 363: Environmental and security problems
Abstract: Aircraft emissions contribute to local and global air pollution. Health effects of particulate matter (PM) from aircraft engines are largely unknown, since controlled cell exposures at relevant conditions are challenging. We examined the toxicity of non-volatile PM (nvPM) emissions from a CFM56-7B26 turbofan, the world's most used aircraft turbine using an unprecedented exposure setup. We combined direct turbine-exhaust sampling under realistic engine operating conditions and the Nano-Aerosol Chamber for In vitro Toxicity to deposit particles onto air-liquid-interface cultures of human bronchial epithelial cells (BEAS-2B) at physiological conditions. We evaluated acute cellular responses after 1-h exposures to diluted exhaust from conventional or alternative fuel combustion. We show that single, short-term exposures to nvPM impair bronchial epithelial cells, and PM from conventional fuel at ground-idle conditions is the most hazardous. Electron microscopy of soot reveals varying reactivity matching the observed cellular responses. Stronger responses at lower mass concentrations suggest that additional metrics are necessary to evaluate health risks of this increasingly important emission source.
Departement: School of Engineering
Organisational Unit: Centre for Aviation (ZAV)
Publication type: Article in scientific journal
DOI : 10.21256/zhaw-5505
ISSN: 2399-3642
Appears in Collections:Publikationen School of Engineering

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