Publication type: Conference paper
Type of review: Not specified
Title: How effect-based activity profiling can contribute to safer irrigation water : the example of the planar-YES
Authors: Schönborn, Andreas
Mainetti, Tamara
Proceedings: Proceedings Xenowac II - Challenges and Solutions Related to Xenobiotics and Antimicrobial Resistance in the Framewaork of Urban Wastewater Reuse
Conference details: XENOWAC II, Limassol, Cyprus, 10-12 October 2018
Issue Date: 2018
Language: English
Subject (DDC): 540: Chemistry
620: Engineering
Abstract: The novel planar-YES bioassay on estrogenic activity is an example for a new type of effect-based research tools that can simultaneously detect, quantify and differentiate a multitude of substances triggering a given receptor. The sensitivity (LOD) of the planar-YES in its current state is around 0.1 ng/l of sample, while offering a number of additional information compared to "classical" YES bioassays performed in microtiter plates. With the work presented here, we aim to demonstrate the type of results and the high potential of this approach at the example of 42 wastewater samples from 26 wastewater treatment plants in 2 Swiss cantons. We are comparing and typifying the activity profiles of found in these wastewater samples and discuss their significance for regulation purposes. The planar-YES development has now reached a state, where market-entry for commercial use is close-by.
Fulltext version: Published version
License (according to publishing contract): Licence according to publishing contract
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Natural Resource Sciences (IUNR)
Appears in collections:Publikationen Life Sciences und Facility Management

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