Title: Simulation of transcatheter aortic valve implantation under consideration of leaflet calcification
Authors : Russ, Christoph
Hopf, Raoul
Hirsch, Sven
Sundermann, Simon
Falk, Volkmar
Szekely, Gabor
Gessat, Michael
Proceedings: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Pages : 711
Pages to: 714
Conference details: 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Osaka, Japan, 3-7 July 2013
Publisher / Ed. Institution : IEEE
Issue Date: 2013
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Publication)
Language : English
Subjects : Stent placement; Aortic valve stenosis; Calcinosis; Cardiomyopathies; Calcification; Stents; Heart valve prosthesis; Transcatheter aortic valve replacement; Biomedical simulation
Subject (DDC) : 610: Medicine and health
617: Surgery
Abstract: Transcatheter aortic valve implantation (TAVI) is a minimally invasive off-pump procedure to replace diseased aortic heart valves. Known complications include paravalvular leaks, atrioventricular blocks, coronary obstruction and annular rupture. Careful procedure planning including appropriate stent selection and sizing are crucial. Few patient-specific geometric parameters, like annular diameters, annular perimeter and measurement of the distance to the coronary ostia, are currently used within this process. Biomechanical simulation allows the consideration of extracted anatomy and material parameters for the intervention, which may improve planning and execution phases. We present a simulation workflow using a fully segmented aortic root anatomy, which was extracted from pre-operative CT-scan data and apply individual material models and parameters to predict the procedure outcome. Our results indicate the high relevance of calcification location and size for intervention planning, which are not sufficiently considered at this time. Our analysis can further provide guidance for accurate, patient-specific device positioning and future adaptations to stent design.
Departement: Life Sciences und Facility Management
Organisational Unit: Institute of Applied Simulation (IAS)
Publication type: Conference Paper
DOI : 10.1109/EMBC.2013.6609599
ISBN: 978-1-4577-0216-7
ISSN: 1094-687X
URI: https://digitalcollection.zhaw.ch/handle/11475/13621
Appears in Collections:Publikationen Life Sciences und Facility Management

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